Ruíz-García Erika, Guadarrama-Orozco Jorge, Vidal-Millán Silvia, Lino-Silva Leonardo S, López-Camarillo César, Astudillo-de la Vega Horacio
a Laboratorio de Medicina Traslacional , Instituto Nacional de Cancerología , Ciudad de México , México.
b Departamento de Tumores Gastro-Intestinales , Instituto Nacional de Cancerología , Ciudad de México , México.
Scand J Gastroenterol. 2018 Feb;53(2):124-129. doi: 10.1080/00365521.2017.1417473. Epub 2017 Dec 23.
Every year, cancer affects more than one million Latin Americans. The increasing incidence of cancer could be secondary to an aging population, westernization of life style, and urbanization. LA has among the highest incidence rates of gastric cancer, compared to other countries. In this review, different studies on gastric cancer and its relation with risks factors, such as infections, diet and life styles typical of LA, besides the different molecular alterations of that specific population (mainly at a genetic polymorphism level) are analyzed. An exhaustive research was made in PubMed, MEDLINE and Embase of the most relevant studies conducted in the last 27 years (1990-2017) in LA.
每年，癌症影响着超过100万拉丁美洲人。癌症发病率的上升可能归因于人口老龄化、生活方式的西方化以及城市化。与其他国家相比，拉丁美洲的胃癌发病率位居前列。在本综述中，分析了关于胃癌及其与风险因素（如感染、拉丁美洲典型的饮食和生活方式）的关系的不同研究，此外还分析了该特定人群的不同分子改变（主要是基因多态性水平）。我们在PubMed、MEDLINE和Embase数据库中对过去27年（1990 - 2017年）在拉丁美洲进行的最相关研究进行了详尽检索。
