Pedersen Malene Roland, Møller Henrik, Osther Palle Jørn Sloth, Vedsted Peter, Holst René, Rafaelsen Søren Rafael
Department of Radiology, Clinical Cancer Centre, Vejle Hospital, Part of Lillebaelt Hospital, Denmark.
Urological Research Centre, Vejle Hospital, Part of Lillebaelt Hospital, Denmark.
Ultrasound Int Open. 2017 Sep;3(4):E150-E155. doi: 10.1055/s-0043-116660. Epub 2017 Dec 20.
To compare elastography measurements in men with normal testicular tissue, testicular microlithiasis and testicular cancer.
A total of 248 consecutive patients were included. All men provided written informed consent. Testicular stiffness was assessed using shear wave elastography (SWE). Three SWE velocity measurements were assessed in each testicle. The patients were divided into three groups; men with normal testicular tissue (n=130), men with testicular microlithiasis (n=99) and men with testicular cancer (n=19).
We found a higher mean velocity in the group of patients with testicular cancer (1.92 m/s (95% CI 1.82-2.03)) compared to both the group with normal tissue (0.76 m/s (95% CI: 0.75-0.78)) (p<0.001) and the group with testicular microlithiasis 0.79 m/s (95% CI: 0.77-0.81) (p<0.001).
The presence of testicular microlithiasis increased stiffness slightly, but within the range of variation in normal testicles. Increased stiffness may indicate testicular malignancy in testicular lesions. Ultrasound elastography could be a very useful tool when investigating scrotum.
比较正常睾丸组织、睾丸微结石症和睾丸癌男性患者的弹性成像测量结果。
共纳入248例连续患者。所有男性均提供了书面知情同意书。使用剪切波弹性成像(SWE)评估睾丸硬度。对每个睾丸进行三次SWE速度测量。患者分为三组:正常睾丸组织男性(n = 130)、睾丸微结石症男性(n = 99)和睾丸癌男性(n = 19)。
我们发现,与正常组织组(0.76 m/s(95%CI:0.75 - 0.78))(p < 0.001)和睾丸微结石症组(0.79 m/s(95%CI:0.77 - 0.81))(p < 0.001)相比,睾丸癌患者组的平均速度更高(1.92 m/s(95%CI 1.82 - 2.03))。
睾丸微结石症的存在会使硬度略有增加,但在正常睾丸的变化范围内。硬度增加可能表明睾丸病变存在恶性肿瘤。超声弹性成像在阴囊检查中可能是一种非常有用的工具。