Naiman Melissa I, Gray Maria, Haymore Joseph, Hegazy Ahmed F, Markota Andrej, Badjatia Neeraj, Kulstad Erik B
Center for Advanced Design, Research, and Exploration, University of Illinois at Chicago; Attune Medical.
Attune Medical.
J Vis Exp. 2017 Nov 21(129):56579. doi: 10.3791/56579.
Controlling patient temperature is important for a wide variety of clinical conditions. Cooling to normal or below normal body temperature is often performed for neuroprotection after ischemic insult (e.g. hemorrhagic stroke, subarachnoid hemorrhage, cardiac arrest, or other hypoxic injury). Cooling from febrile states treats fever and reduces the negative effects of hyperthermia on injured neurons. Patients are warmed in the operating room to prevent inadvertent perioperative hypothermia, which is known to cause increased blood loss, wound infections, and myocardial injury, while also prolonging recovery time. There are many reported approaches for temperature management, including improvised methods that repurpose standard supplies (e.g., ice, chilled saline, fans, blankets) but more sophisticated technologies designed for temperature management are typically more successful in delivering an optimized protocol. Over the last decade, advanced technologies have developed around two heat transfer methods: surface devices (water blankets, forced-air warmers) or intravascular devices (sterile catheters requiring vascular placement). Recently, a novel device became available that is placed in the esophagus, analogous to a standard orogastric tube, that provides efficient heat transfer through the patient's core. The device connects to existing heat exchange units to allow automatic patient temperature management via a servo mechanism, using patient temperature from standard temperature sensors (rectal, Foley, or other core temperature sensors) as the input variable. This approach eliminates vascular placement complications (deep venous thrombosis, central line associated bloodstream infection), reduces obstruction to patient access, and causes less shivering when compared to surface approaches. Published data have also shown a high degree of accuracy and maintenance of target temperature using the esophageal approach to temperature management. Therefore, the purpose of this method is to provide a low-risk alternative method for controlling patient temperature in critical care settings.
控制患者体温对于多种临床情况都很重要。在缺血性损伤(如出血性中风、蛛网膜下腔出血、心脏骤停或其他缺氧性损伤)后,常进行降温至正常或低于正常体温以实现神经保护。从发热状态降温可治疗发热,并减少高热对受损神经元的负面影响。在手术室中对患者进行升温以防止围手术期意外低温,已知低温会导致失血增加、伤口感染和心肌损伤,同时还会延长恢复时间。有许多报道的体温管理方法,包括重新利用标准用品的简易方法(如冰、冷盐水、风扇、毯子),但专为体温管理设计的更复杂技术通常在实施优化方案方面更成功。在过去十年中,先进技术围绕两种热传递方法发展:体表设备(水毯、强制空气加温器)或血管内设备(需要血管置管的无菌导管)。最近,一种新型设备问世,它放置在食管中,类似于标准的口胃管,可通过患者核心部位实现高效热传递。该设备连接到现有的热交换单元,通过伺服机制实现患者体温的自动管理,将来自标准温度传感器(直肠、弗利导管或其他核心温度传感器)的患者体温作为输入变量。与体表方法相比,这种方法消除了血管置管并发症(深静脉血栓形成、中心静脉导管相关血流感染),减少了对患者通路的阻碍,并且引起的寒战较少。已发表的数据还表明,使用食管体温管理方法具有高度的准确性和目标温度维持能力。因此,该方法的目的是在重症监护环境中提供一种低风险的控制患者体温的替代方法。