替代策略预防布鲁氏菌病疫苗接种。
Alternative strategies for vaccination to brucellosis.
机构信息
Department of Infectious Diseases & Immunology, College of Veterinary Medicine, University of Florida, Gainesville, FL, 32611, USA.
Department of Infectious Diseases & Immunology, College of Veterinary Medicine, University of Florida, Gainesville, FL, 32611, USA.
出版信息
Microbes Infect. 2018 Oct-Nov;20(9-10):599-605. doi: 10.1016/j.micinf.2017.12.006. Epub 2017 Dec 26.
Abstract
Brucellosis remains burdensome for livestock and humans worldwide. Better vaccines for protection are needed to reduce disease incidence. Immunity to brucellosis and barriers to protection are discussed. The benefits and limitations of conventional and experimental brucellosis vaccines are outlined, and novel vaccination strategies needed to ultimately protect against brucellosis are introduced.
摘要
布氏杆菌病仍然是全世界家畜和人类的沉重负担。需要更好的疫苗来减少疾病的发生。本文讨论了对布氏杆菌病的免疫和保护障碍。概述了常规和实验性布氏杆菌病疫苗的优缺点，并介绍了最终预防布氏杆菌病所需的新型疫苗接种策略。
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