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脊髓蛛网膜憩室手术后迟发性神经功能缺损复发

Late-onset recurrence of neurological deficits after surgery for spinal arachnoid diverticula.

作者信息

Alcoverro Emili, McConnell James Fraser, Sanchez-Masian Daniel, De Risio Luisa, De Decker Steven, Gonçalves Rita

机构信息

Institute of Veterinary Science, Small Animal Teaching Hospital, University of Liverpool, Neston, UK.

Department of Neurology and Neurosurgery, The Animal Health Trust, Suffolk, UK.

出版信息

Vet Rec. 2018 Mar 31;182(13):380. doi: 10.1136/vr.104579. Epub 2017 Dec 29.

Abstract

Spinal cord dysfunction secondary to spinal arachnoid diverticula (SAD) has been widely reported in the veterinary literature and there is some suggestion that surgical treatment may provide better outcomes than medical treatment. Despite this, previous reports have mentioned cases with recurrence of clinical signs following surgical treatment but the cause for this has not been further investigated. The medical records of seven dogs and one cat which presented for investigation of recurrence of neurological deficits at least six months after surgery for SAD were retrospectively reviewed. Median time to relapse of the neurological deficits was 20.5 months after surgery. On repeated imaging, 3/8 cases showed clear regrowth of diverticulum, 2/8 cases showed dorsal compression at the previous laminectomy site (presumed to be the laminectomy membrane), and 3/8 cases showed herniation of the spinal cord through the laminectomy defect associated with a stellate appearance to the spinal cord with small multiloculated areas of dilation of the subarachnoid space. Repeat surgical intervention was most successful in the cases where SAD recurrence was identified while medical treatment resulted in either subtle improvement or stabilisation on the clinical signs, sometimes followed by slow deterioration.

摘要

继发于脊髓蛛网膜憩室(SAD)的脊髓功能障碍在兽医文献中已有广泛报道,并且有迹象表明手术治疗可能比药物治疗效果更好。尽管如此,先前的报告提到了一些病例,在手术治疗后临床症状复发,但尚未对其原因进行进一步调查。对7只狗和1只猫的病历进行了回顾性研究,这些动物在接受SAD手术后至少6个月因神经功能缺损复发前来接受调查。神经功能缺损复发的中位时间为术后20.5个月。在重复成像时,3/8的病例显示憩室明显再生,2/8的病例显示在先前椎板切除部位(推测为椎板切除膜)出现背侧压迫,3/8的病例显示脊髓通过椎板切除缺损疝出,伴有脊髓呈星状外观以及蛛网膜下腔小的多房性扩张区域。在确定SAD复发的病例中,重复手术干预最为成功,而药物治疗则使临床症状出现轻微改善或稳定,有时随后会缓慢恶化。

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