无中生有：过度通气引发的癫痫发作。
Out of thin air: Hyperventilation-triggered seizures.
机构信息
Department of Pharmacology, University of Virginia School of Medicine, Charlottesville, VA 22903, United States.
Department of Pharmacology, University of Virginia School of Medicine, Charlottesville, VA 22903, United States.
出版信息
Brain Res. 2019 Jan 15;1703:41-52. doi: 10.1016/j.brainres.2017.12.037. Epub 2017 Dec 27.
Abstract
Voluntary hyperventilation triggers seizures in the vast majority of people with absence epilepsy. The mechanisms that underlie this phenomenon remain unknown. Herein, we review observations - many made long ago - that provide insight into the relationship between breathing and absence seizures.
摘要
自主过度通气会引发绝大多数失神癫痫患者的发作。其背后的机制尚不清楚。在此，我们回顾了许多很久以前的观察结果，这些结果为呼吸与失神发作之间的关系提供了一些见解。
相似文献
1
Out of thin air: Hyperventilation-triggered seizures.无中生有：过度通气引发的癫痫发作。
Brain Res. 2019 Jan 15;1703:41-52. doi: 10.1016/j.brainres.2017.12.037. Epub 2017 Dec 27.
2
Cerebral metabolism during epileptic seizures in man.
Electroencephalogr Clin Neurophysiol. 1966 Jul;21(1):10-22. doi: 10.1016/0013-4694(66)90054-x.
3
Will a critical level of hyperventilation-induced hypocapnia always induce an absence seizure?过度通气诱发的低碳酸血症达到临界水平时总会引发失神发作吗？
Epilepsia. 1996 May;37(5):459-62. doi: 10.1111/j.1528-1157.1996.tb00592.x.
4
Pharmacological profiles of absence seizure-induced increases in CRE- and AP-1 DNA-binding activities in gamma-butyrolactone-treated mice.
Nihon Shinkei Seishin Yakurigaku Zasshi. 1998 Aug;18(4):117-22.
5
Genetic absence epilepsy rats from Strasbourg have increased corticothalamic expression of stargazin.来自斯特拉斯堡的遗传性失神癫痫大鼠，其皮质丘脑的stargazin表达增加。
Neurobiol Dis. 2008 Aug;31(2):261-5. doi: 10.1016/j.nbd.2008.04.012. Epub 2008 May 10.
6
Modulation of absence seizures by branched-chain amino acids: correlation with brain amino acid concentrations.支链氨基酸对失神发作的调节作用：与脑内氨基酸浓度的相关性。
Neurosci Res. 2001 Jul;40(3):255-63. doi: 10.1016/s0168-0102(01)00232-2.
7
Developmental changes of GABA immunoreactivity in cortico-thalamic networks of an absence seizure model.发育过程中 GABA 免疫反应在失神性癫痫模型皮质丘脑网络中的变化。
Neuropharmacology. 2018 Jul 1;136(Pt A):56-67. doi: 10.1016/j.neuropharm.2018.01.047. Epub 2018 Feb 19.
8
Regulation of gamma-aminobutyric acid (GABA) release in cerebral cortex in the gamma-hydroxybutyric acid (GHB) model of absence seizures in rat.大鼠失神发作的γ-羟基丁酸（GHB）模型中大脑皮层γ-氨基丁酸（GABA）释放的调节
Neuropharmacology. 2000 Jan 28;39(3):427-39. doi: 10.1016/s0028-3908(99)00152-5.
9
Respiratory alkalosis provokes spike-wave discharges in seizure-prone rats.呼吸性碱中毒可引发易发生癫痫的大鼠出现棘波放电。
Elife. 2022 Jan 4;11:e72898. doi: 10.7554/eLife.72898.
10
5% CO₂ inhalation suppresses hyperventilation-induced absence seizures in children.吸入 5% 的二氧化碳可抑制儿童过度通气引起的失神发作。
Epilepsy Res. 2014 Feb;108(2):345-8. doi: 10.1016/j.eplepsyres.2013.11.012. Epub 2013 Nov 20.
引用本文的文献
1
Heartbeat-evoked potentials following voluntary hyperventilation in epilepsy patients: respiratory influences on cardiac interoception.癫痫患者自主过度通气后的心跳诱发电位：呼吸对心脏内感受的影响。
Front Neurosci. 2024 Jul 5;18:1391437. doi: 10.3389/fnins.2024.1391437. eCollection 2024.
2
Juvenile idiopathic epilepsy in Egyptian Arabian foals, a potential animal model of self-limited epilepsy in children.埃及阿拉伯小马驹的青少年特发性癫痫，儿童自限性癫痫的潜在动物模型。
J Vet Intern Med. 2024 Jan-Feb;38(1):449-459. doi: 10.1111/jvim.16965. Epub 2023 Dec 2.
3
A Case of Panic Disorder Misdiagnosed as Epilepsy for 9 Years in a Young Male.一名青年男性惊恐障碍被误诊为癫痫9年的病例。
Saudi J Med Med Sci. 2023 Apr-Jun;11(2):175-177. doi: 10.4103/sjmms.sjmms_313_22. Epub 2023 Apr 12.
4
Thalamocortical circuits in generalized epilepsy: Pathophysiologic mechanisms and therapeutic targets.广泛性癫痫的丘脑皮质电路：病理生理机制和治疗靶点。
Neurobiol Dis. 2023 Jun 1;181:106094. doi: 10.1016/j.nbd.2023.106094. Epub 2023 Mar 27.
5
Near-Infrared Spectroscopy Usefulness in Validation of Hyperventilation Test.近红外光谱在过度通气试验验证中的作用。
Medicina (Kaunas). 2022 Oct 6;58(10):1396. doi: 10.3390/medicina58101396.
6
Combined Fainting and Psychogenic Non-epileptic Seizures as Significant Therapy Hurdles in Blood-Injury-Injection Phobia: A Mini-Review and Case Report.晕厥与心因性非癫痫性发作合并存在作为血液-损伤-注射恐惧症重要的治疗障碍：一项小型综述及病例报告
Front Psychiatry. 2022 Jul 12;13:915058. doi: 10.3389/fpsyt.2022.915058. eCollection 2022.
7
Occurrence of hyperventilation-induced high amplitude rhythmic slowing with altered awareness after successful treatment of typical absence seizures and a network hypothesis.典型失神发作成功治疗后出现通气过度诱发的高幅节律性慢波伴意识改变及网络假说
Clin Neurophysiol Pract. 2021 Jun 11;6:185-188. doi: 10.1016/j.cnp.2021.03.009. eCollection 2021.
8
Physiologic Implications of Reactive Oxygen Species Production by Mitochondrial Complex I Reverse Electron Transport.线粒体复合物I逆向电子传递产生活性氧的生理意义
Antioxidants (Basel). 2019 Aug 6;8(8):285. doi: 10.3390/antiox8080285.
本文引用的文献
1
Pathophysiology of absence epilepsy: Insights from genetic models.失神癫痫的病理生理学：来自遗传模型的见解。
Neurosci Lett. 2018 Feb 22;667:53-65. doi: 10.1016/j.neulet.2017.02.035. Epub 2017 Feb 16.
2
Absence epilepsy: Continuum of clinical presentation and epigenetics?失神癫痫：临床表现与表观遗传学的连续统一体？
Seizure. 2017 Jan;44:53-57. doi: 10.1016/j.seizure.2016.11.031. Epub 2016 Dec 6.
3
Tapping the Brakes: Cellular and Synaptic Mechanisms that Regulate Thalamic Oscillations.轻点刹车：调节丘脑振荡的细胞与突触机制
Neuron. 2016 Nov 23;92(4):687-704. doi: 10.1016/j.neuron.2016.10.024.
4
Timing of high-frequency cortical stimulation in a genetic absence model.遗传性失神模型中高频皮层刺激的时机
Neuroscience. 2016 Jun 2;324:191-201. doi: 10.1016/j.neuroscience.2016.02.070. Epub 2016 Mar 8.
5
A call to arms against "The Phantom of Epilepsy".
Epilepsia. 2015 Nov;56(11):1710-1. doi: 10.1111/epi.13197. Epub 2015 Sep 28.
6
Acute and chronic pharmacological models of generalized absence seizures.全身性失神发作的急性和慢性药理学模型。
J Neurosci Methods. 2016 Feb 15;260:175-84. doi: 10.1016/j.jneumeth.2015.08.034. Epub 2015 Sep 5.
7
Long-term outcomes of generalized tonic-clonic seizures in a childhood absence epilepsy trial.一项儿童失神癫痫试验中全身强直阵挛发作的长期预后
Neurology. 2015 Sep 29;85(13):1108-14. doi: 10.1212/WNL.0000000000001971. Epub 2015 Aug 26.
8
CaV3.2 calcium channels control NMDA receptor-mediated transmission: a new mechanism for absence epilepsy.CaV3.2钙通道控制N-甲基-D-天冬氨酸受体介导的传递：失神癫痫的一种新机制。
Genes Dev. 2015 Jul 15;29(14):1535-51. doi: 10.1101/gad.260869.115.
9
The genetic absence epilepsy rat from Strasbourg as a model to decipher the neuronal and network mechanisms of generalized idiopathic epilepsies.来自斯特拉斯堡的遗传性失神癫痫大鼠作为一种模型，用于解读全身性特发性癫痫的神经元和网络机制。
J Neurosci Methods. 2016 Feb 15;260:159-74. doi: 10.1016/j.jneumeth.2015.05.022. Epub 2015 Jun 9.
10
Altered thalamocortical rhythmicity and connectivity in mice lacking CaV3.1 T-type Ca2+ channels in unconsciousness.缺乏CaV3.1 T型Ca2+通道的小鼠在无意识状态下丘脑皮质节律性和连接性的改变
Proc Natl Acad Sci U S A. 2015 Jun 23;112(25):7839-44. doi: 10.1073/pnas.1420983112. Epub 2015 Jun 8.
Zotero 插件