Cianchetti Carlo, Bianchi Elisa, Guerrini Renzo, Baglietto Maria Giuseppina, Briguglio Marilena, Cappelletti Simona, Casellato Susanna, Crichiutti Giovanni, Lualdi Rosa, Margari Lucia, Romeo Antonino, Beghi Ettore
Child and Adolescent Neuropsychiatry, University of Cagliari, Italy.
Department of Neuroscience, Istituto di Ricerche Farmacologiche "Mario Negri", IRCCS, Milano, Italy.
Epilepsy Behav. 2018 Feb;79:146-153. doi: 10.1016/j.yebeh.2017.11.030. Epub 2018 Jan 4.
We studied children and adolescents with epilepsy (CAWE) and their families to evaluate symptoms of anxiety and depression, quality of life (QoL), and their correlations with epilepsy characteristics.
The study included 326 (52.5% females) 8 to 18years old CAWE. Anxiety and depression were assessed with the "Self-administered psychiatric scales for children and adolescents" (SAFA), and family's QoL with the parents' report "Impact of Epilepsy on QoL" (IEQoL).
The CAWE exhibiting abnormal (T≥70) scores were 8.0% in the anxiety scale, 9.2% in the depression scale, and 4.6% in both scales. Social anxiety was the predominant anxiety symptom, while irritable mood and desperation were the most frequent symptoms of depression. Depressive symptoms were associated with parents' complaint of higher worries about the child's condition and future and lower well-being of the family. Severity and duration of the epilepsy and polypharmacy were independent from abnormal scores of anxiety and depression, but were associated with parents' worries about the child's condition and family's well-being.
Anxiety and depression in CAWE are independent from the characteristics of the disease but are correlated to the lower well-being of the family. A search of these emotional problems is recommended for better care of the patients and their families.
我们对患有癫痫的儿童和青少年（CAWE）及其家庭进行了研究，以评估焦虑和抑郁症状、生活质量（QoL），以及它们与癫痫特征的相关性。
该研究纳入了326名8至18岁的CAWE（女性占52.5%）。使用“儿童和青少年自评精神量表”（SAFA）评估焦虑和抑郁情况，通过父母报告的“癫痫对生活质量的影响”（IEQoL）评估家庭生活质量。
在焦虑量表中，CAWE得分异常（T≥70）的比例为8.0%，抑郁量表中为9.2%，两个量表均异常的比例为4.6%。社交焦虑是主要的焦虑症状，而烦躁情绪和绝望是最常见的抑郁症状。抑郁症状与父母对孩子病情和未来的更高担忧以及家庭幸福感较低有关。癫痫的严重程度、持续时间和联合用药与焦虑和抑郁的异常得分无关，但与父母对孩子病情的担忧和家庭幸福感有关。
CAWE中的焦虑和抑郁与疾病特征无关，但与家庭幸福感较低有关。建议对这些情绪问题进行排查，以便更好地照顾患者及其家庭。
