Chen Dugang, Chen Pengyu, Zong Luyi, Sun Yimin, Liu Guangchao, Yu Xianglin, Qin Jingui
Key Laboratory for Green Chemical Process of Ministry of Education, School of Chemical Engineering and Pharmacy, Wuhan Institute of Technology, Wuhan 430205, People's Republic of China.
College of Chemistry and Molecular Science, Wuhan University, Wuhan 430072, People's Republic of China.
R Soc Open Sci. 2017 Nov 8;4(11):171161. doi: 10.1098/rsos.171161. eCollection 2017 Nov.
In this paper, BT (()-2-(4-(4-(bis(pyridin-2-ylmethyl)amino)styryl)-3-cyano-5,5-dimethylfuran-2(5H)-ylidene)malononitrile) with strong donor-π-acceptor structure was synthesized, which showed both colorimetric and fluorescent sensing ability toward Cu with high selectivity and sensitivity. Job plot and mass spectra measurement revealed a 1 : 1 coordination mode between Cu and probe BT in ethanol/HEPES (1 : 4 v/v) buffer (pH 7.2) solution, and the binding constant was calculated to be 3.6 × 10 M. The colour of BT solution (10 µM) immediately turned from purple red to yellow and the red fluorescence was quenched obviously when a certain amount of Cu was added, which enabled a dual-channel detection of Cu. A paper strip pre-stained with BT solution was further fabricated and it also showed excellent sensing ability toward Cu with a detection limit as low as 10 M with the naked eye, which represents better portability and operation simplicity that is favourable for on-site analysis of Cu in water.
本文合成了具有强给体-π-受体结构的BT（()-2-(4-(4-(双(吡啶-2-基甲基)氨基)苯乙烯基)-3-氰基-5,5-二甲基呋喃-2(5H)-亚基)丙二腈），其对铜具有比色和荧光传感能力，选择性和灵敏度高。Job曲线和质谱测量表明，在乙醇/HEPES（1 : 4 v/v）缓冲液（pH 7.2）溶液中，铜与探针BT的配位模式为1 : 1，计算得到的结合常数为3.6 × 10 M。加入一定量的铜后，BT溶液（10 µM）的颜色立即从紫红色变为黄色，红色荧光明显猝灭，实现了对铜的双通道检测。进一步制备了用BT溶液预染色的纸条，其对铜也表现出优异的传感能力，肉眼检测限低至10 M，具有更好的便携性和操作简便性，有利于水中铜的现场分析。
