Kim K, Elbuluk A, Yu S, Iorio R
NYU Langone Medical Centre, Hospital for Joint Diseases, 301 E 17th Street, New York, NY 10003, USA.
Bone Joint J. 2018 Jan;100-B(1 Supple A):55-61. doi: 10.1302/0301-620X.100B1.BJJ-2017-0549.R1.
The aim of this study was to determine the optimal regimen for the management of pain following total knee arthroplasty (TKA) by comparing the outcomes and cost-effectiveness of different protocols implemented at a large, urban, academic medical centre.
Between September 2013 and September 2015, we used a series of modifications to our standard regimen for the management of pain after TKA. In May 2014, there was a department-wide transition from protocols focused on femoral nerve blocks (FNB) to periarticular injections of liposomal bupivacaine. In February 2015, patient-controlled analgesia (PCA) was removed from the protocol while continuing liposomal bupivacaine injections. Quality measures and hospital costs were compared between the three protocols.
The cohort being treated with PCA-less liposomal bupivacaine injections had a significantly higher percentage of patients who were discharged to their home (p = 0.010) and a significantly shorter length of stay (p < 0.001). Patient-reported Hospital Consumer Assessment of Healthcare Providers and Systems (HCAHPS) scores relating to pain being "well-controlled" and "overall pain management" also favoured this cohort (p = 0.214 and p = 0.463, respectively), in which cost was significantly lower compared with the other two cohorts (p = 0.005).
The replacement of FNBs injections and the removal of PCAs, both of which are known to be associated with high rates of adverse outcomes, and the addition of liposomal bupivacaine periarticular injections to a multimodal pain regimen, led to improvements in many quality measures, HCAHPS pain scores, and cost-effectiveness. Cite this article: 2018;100-B(1 Supple A):55-61.
本研究旨在通过比较在一家大型城市学术医疗中心实施的不同方案的结果和成本效益,确定全膝关节置换术(TKA)后疼痛管理的最佳方案。
2013年9月至2015年9月期间,我们对TKA后疼痛管理的标准方案进行了一系列修改。2014年5月,全科室从专注于股神经阻滞(FNB)的方案过渡到关节周围注射脂质体布比卡因。2015年2月,在继续脂质体布比卡因注射的同时,从方案中取消了患者自控镇痛(PCA)。比较了三种方案之间的质量指标和医院成本。
接受无PCA脂质体布比卡因注射治疗的队列中,出院回家的患者比例显著更高(p = 0.010),住院时间显著更短(p < 0.001)。患者报告的与疼痛“得到良好控制”和“总体疼痛管理”相关的医疗服务提供者和系统医院消费者评估(HCAHPS)分数也有利于该队列(分别为p = 0.214和p = 0.463),其中成本与其他两个队列相比显著更低(p = 0.005)。
已知与高不良结局发生率相关的FNB注射的替代以及PCA的取消,以及在多模式疼痛方案中添加脂质体布比卡因关节周围注射,导致许多质量指标、HCAHPS疼痛评分和成本效益得到改善。引用本文:2018;100-B(1增刊A):55-61。