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[308纳米准分子激光:白癜风和色素减退的治疗]

[The 308 nm Excimer laser : Treatment of vitiligo and hypopigmentation].

作者信息

Fritz K, Salavastru C

机构信息

Hautärzte- und Laserzentrum Landau (Pfalz), Reduitstr. 13, 76829, Landau, Deutschland.

Medizinische und Pharmazeutische Universität Carol Davila, Bucharest, Rumänien.

出版信息

Hautarzt. 2018 Jan;69(1):44-47. doi: 10.1007/s00105-017-4097-y.

DOI:10.1007/s00105-017-4097-y
PMID:29294169
Abstract

Use of the 308 nm Excimer laser to treat hypopigmentation and vitiligo is usually superior to conventional ultraviolet (UV) therapy with regard to results and safety. It is particularly advantageous because specific areas of skin can be targeted without burdening the rest of the skin. Fewer sessions with lower cumulative doses are required. Various combination therapies can improve the outcome; selection criteria such as early initiation of treatment and more frequent sessions with shorter intervals make it easier to decide which patients should be treated and how to achieve the greatest benefit.

摘要

使用308纳米准分子激光治疗色素减退和白癜风,在疗效和安全性方面通常优于传统紫外线(UV)疗法。它特别具有优势,因为可以靶向皮肤的特定区域,而不会给其余皮肤带来负担。所需治疗次数更少,累积剂量更低。各种联合疗法可以改善治疗效果;诸如尽早开始治疗以及更频繁地进行治疗且间隔时间更短等选择标准,使得更容易确定哪些患者应该接受治疗以及如何获得最大益处。

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本文引用的文献

1
Improvement in moderate to severe vitiligo using a novel combination of 308 nm excimer laser and a surgical needling technique.采用新型308纳米准分子激光与手术针刺技术联合治疗中重度白癜风的疗效观察
Clin Exp Dermatol. 2017 Apr;42(3):363-366. doi: 10.1111/ced.13056.
2
Treatment of vitiligo with 308-nm excimer laser: our experience from a 2-year follow-up of 979 Chinese patients.308纳米准分子激光治疗白癜风:对979例中国患者进行2年随访的经验
J Eur Acad Dermatol Venereol. 2017 Feb;31(2):337-340. doi: 10.1111/jdv.13917. Epub 2016 Sep 19.
3
The efficacy of 308-nm excimer laser/light (EL) and topical agent combination therapy versus EL monotherapy for vitiligo: A systematic review and meta-analysis of randomized controlled trials (RCTs).
308nm 准分子激光/光(EL)与局部药物联合治疗与 EL 单药治疗白癜风的疗效比较:一项随机对照试验(RCT)的系统评价和荟萃分析。
J Am Acad Dermatol. 2016 May;74(5):907-15. doi: 10.1016/j.jaad.2015.11.044. Epub 2016 Jan 16.
4
A combination of excimer laser treatment and topical tacrolimus is more effective in treating vitiligo than either therapy alone for the initial 6 months, but not thereafter.在治疗白癜风方面,准分子激光治疗与外用他克莫司联合使用在最初6个月比单独使用任何一种疗法都更有效,但6个月后并非如此。
Clin Exp Dermatol. 2016 Apr;41(3):236-41. doi: 10.1111/ced.12742. Epub 2015 Aug 24.
5
Effect of an antioxydant cream versus placebo in patients with vitiligo in association with excimer laser. A pilot randomized, investigator-blinded, and half-side comparison trial.抗氧化乳膏与安慰剂对白癜风患者联合准分子激光治疗的效果。一项前瞻性随机、研究者设盲及半侧对照试验。
G Ital Dermatol Venereol. 2015 Aug;150(4):461-6.
6
Effectiveness of a 308-nm excimer laser in treatment of vitiligo: a review.308nm 准分子激光治疗白癜风的疗效评价:综述。
Lasers Med Sci. 2013 May;28(3):1035-41. doi: 10.1007/s10103-012-1185-1. Epub 2012 Aug 15.
7
Vitiligo treatment with monochromatic excimer light and tacrolimus: results of an open randomized controlled study.单色准分子光联合他克莫司治疗白癜风:一项开放性随机对照研究的结果
Photomed Laser Surg. 2012 Jan;30(1):26-30. doi: 10.1089/pho.2011.3029. Epub 2011 Nov 4.
8
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J Clin Aesthet Dermatol. 2011 Jun;4(6):41-4.
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