Zhao H Y, Yang J, Sun F, Yang X H, Yang Z R, Wang S F, Zhan S Y
Department of Epidemiology and Biostatistics, School of Public Health, Peking University, Beijing 100191, China.
Department of Epidemiology and Biostatistics, School of Public Health, Capital Medical University, Beijing 100069, China.
Zhonghua Liu Xing Bing Xue Za Zhi. 2017 Dec 10;38(12):1591-1597. doi: 10.3760/cma.j.issn.0254-6450.2017.12.001.
To explore the risk of developing metabolic syndrome (MS) by using the data from cohorts involving people having received screening programs for physical check-up, in three areas of China (Beijing, Hongkong and Taiwan). A total number of 6 828 nonmetabolic syndromic adults, who received physical examination for the first time and with records kept for longer than 5 years (between 2004 and 2010) at the MJ centers, were recruited. Criteria developed by the Joint Committee for Developing Chinese Guidelines on Prevention and Treatment of Dyslipidemia in Chinese Adults in 2007 (JCDCG-2007) was used for defining the metabolic syndrome. Cox proportional hazards regression model was used to examine the difference of the risk of developing MS among the three cohorts that received the health screening programs. The standardized incidence densities of MS were 3.14 per 100 person-years, 2.19 per 100 person-years and 2.03 per 100 person-years in the cohorts of Beijing, Hongkong and Taiwan, respectively. After adjusting for gender, age, cigarette smoking, dietary patterns at the baseline, the s for people in Beijing and Hongkong were 1.60 (95%: 1.34-1.91) and 1.08 (95%: 0.83-1.41) respectively, in developing MS, when compared with people from Taiwan. Factors as being male, elderly, cigarette smoking, meat/food intake dietary pattern and MS components at the baseline all showed significantly positive effects on the risk of developing MS. There were significant differences regarding the risk of developing MS among health screening people from the Beijing, Hongkong and Taiwan. Factors as being male, elderly, cigarette smoking, meat/food intake, dietary pattern and MS components at the baseline appear to be the risk factors for developing the MS.
利用来自中国三个地区(北京、香港和台湾)参与体检筛查项目人群的队列数据,探讨发生代谢综合征(MS)的风险。共招募了6828名无代谢综合征的成年人,他们在美兆体检中心首次接受体检,且记录保存时间超过5年(2004年至2010年)。采用2007年中国成人血脂异常防治指南联合委员会制定的标准(JCDCG - 2007)来定义代谢综合征。使用Cox比例风险回归模型来检验接受健康筛查项目的三个队列发生MS风险的差异。北京、香港和台湾队列中MS的标准化发病密度分别为每100人年3.14例、每100人年2.19例和每100人年2.03例。在调整性别、年龄、吸烟情况、基线饮食模式后,与台湾人群相比,北京和香港人群发生MS的风险比分别为1.60(95%可信区间:1.34 - 1.91)和1.08(95%可信区间:0.83 - 1.41)。男性、老年人、吸烟、肉类/食物摄入饮食模式以及基线时的MS组分等因素对发生MS的风险均显示出显著的正向影响。北京、香港和台湾接受健康筛查人群发生MS的风险存在显著差异。男性、老年人、吸烟、肉类/食物摄入、饮食模式以及基线时的MS组分等因素似乎是发生MS的危险因素。