Roham Maryam, Momeni Mahnoush, Saberi Mohsen, Kheirkhah Rahil, Jafarian Ali, Rahbar Hossein
Burn Research Center, Iran University of Medical Sciences, Motahari Burn Hospital, Tehran, Iran.
Rowan University Graduate School of Biomedical Sciences, New Jersey, USA.
Iran J Microbiol. 2017 Oct;9(5):271-276.
Currently, there are no well-defined guidelines or criteria for catheter-site care in burn patients, and there is little information about the epidemiology of central vein catheter (CVC) infection in such patients. This study aimed at addressing the epidemiological aspect of CVC infection in a sample of Iranian burn patients admitted to the largest referral burn center in Iran, Motahari Burn Center.
A total of 191 burn patients were eligible for the study. Catheter related blood stream infection (CRBSI) was diagnosed according to suspected line infection, sepsis or blood culture growing bacteria, which could not have been associated with another site.
Of the 191 patients in this study, 45 males (23.68%) and 19 females (10%) had positive blood culture, confirming CV line infection. Patients who were burned by gas, gasoline ignition or burning Kerosene had the highest incidence of CV line infection. In contrast, patients burned by alcohol, pitch or thinner had the lower rate of CV line infection. Incidence of CV line infection was higher in patients with delay in presentation to the burn center (55.2%) when compared to those who presented without delay (22.8%). was the most frequent colonizer of the wound culture (52.4%), the dominant strain of the first catheter tip culture (35%) and the dominant strain of the same day blood samples (53.8%). The mortality rate in patients diagnosed with CRBI was 21.9%.
One of the important factors related to CV line infection is delay inpresentation to the burn center. The rate of CV line infection was 20.64 in catheter days.
目前，对于烧伤患者的导管部位护理，尚无明确的指南或标准，且关于此类患者中心静脉导管（CVC）感染的流行病学信息较少。本研究旨在探讨伊朗最大的烧伤转诊中心——莫塔哈里烧伤中心收治的伊朗烧伤患者样本中CVC感染的流行病学情况。
共有191例烧伤患者符合研究条件。根据疑似导管感染、败血症或血培养出细菌（且与其他部位无关）来诊断导管相关血流感染（CRBSI）。
本研究的191例患者中，45例男性（23.68%）和19例女性（10%）血培养呈阳性，证实存在中心静脉导管感染。因气体、汽油着火或煤油烧伤的患者中心静脉导管感染发生率最高。相比之下，因酒精、沥青或稀释剂烧伤的患者中心静脉导管感染率较低。与未延迟就诊的患者（22.8%）相比，延迟到烧伤中心就诊的患者中心静脉导管感染发生率更高（55.2%）。 是伤口培养中最常见的定植菌（52.4%）、首次导管尖端培养的优势菌株（35%）以及同日血样的优势菌株（53.8%）。诊断为CRBI的患者死亡率为21.9%。
与中心静脉导管感染相关的重要因素之一是延迟到烧伤中心就诊。导管日的中心静脉导管感染率为20.64。
