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Successful combined antibiotic therapy with oral clindamycin and oral rifampicin for pyoderma gangrenosum in patient with PASH syndrome.

作者信息

Lamiaux Marie, Dabouz Fadia, Wantz Maud, Lebas Damien, Lasek Audrey, Courivaud Domitille, Modiano Philippe

机构信息

Department of Dermatology, St Vincent de Paul Hospital, Lille, France.

Lille Catholic University, Lille, France.

出版信息

JAAD Case Rep. 2017 Dec 18;4(1):17-21. doi: 10.1016/j.jdcr.2017.05.005. eCollection 2018 Jan.

DOI:10.1016/j.jdcr.2017.05.005
PMID:29296643
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5739174/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4a86/5739174/00ad56dbbe1e/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4a86/5739174/e95b839c131f/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4a86/5739174/c82cb8ba4935/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4a86/5739174/00ad56dbbe1e/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4a86/5739174/e95b839c131f/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4a86/5739174/c82cb8ba4935/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4a86/5739174/00ad56dbbe1e/gr3.jpg

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本文引用的文献

1
Remission of refractory pyoderma gangrenosum, severe acne, and hidradenitis suppurativa (PASH) syndrome using targeted antibiotic therapy in 4 patients.4 例应用靶向抗生素治疗难治性坏疽性脓皮病、重度痤疮和化脓性汗腺炎（PASH）综合征患者的缓解情况。
J Am Acad Dermatol. 2015 Nov;73(5 Suppl 1):S66-9. doi: 10.1016/j.jaad.2015.07.040.
2
[Developments in pyoderma gangrenosum therapy in 2015].2015年坏疽性脓皮病治疗进展
Ann Dermatol Venereol. 2015 Aug-Sep;142(8-9):502-5. doi: 10.1016/j.annder.2015.06.007. Epub 2015 Jul 10.
3
Treatment of refractory Crohn's disease and pyoderma gangrenosum with a combination regimen of rifaximin, gentamicin and metronidazole.
坏疽性脓皮病和肿瘤坏死因子-α抑制剂：半系统综述。
Int Wound J. 2019 Apr;16(2):511-521. doi: 10.1111/iwj.13067. Epub 2019 Jan 3.
利福昔明、庆大霉素和甲硝唑联合方案治疗难治性克罗恩病和坏疽性脓皮病
Case Rep Gastroenterol. 2015 Jan 24;9(1):25-8. doi: 10.1159/000369965. eCollection 2015 Jan-Apr.
4
First nicastrin mutation in PASH (pyoderma gangrenosum, acne and suppurative hidradenitis) syndrome.PASH（坏疽性脓皮病、痤疮和化脓性汗腺炎）综合征中的首个尼卡斯特林突变。
Br J Dermatol. 2015 Aug;173(2):610-2. doi: 10.1111/bjd.13668. Epub 2015 Jun 11.
5
Successful treatment of PASH syndrome with infliximab, cyclosporine and dapsone.成功使用英夫利昔单抗、环孢素和氨苯砜治疗 PAS 综合征。
J Eur Acad Dermatol Venereol. 2015 Nov;29(11):2243-7. doi: 10.1111/jdv.12765. Epub 2014 Oct 28.
6
Finally, recurrent pyoderma gangrenosum treated with Adalimumab: case report and review of the literature.最后，阿达木单抗治疗复发性坏疽性脓皮病：病例报告及文献综述
J Eur Acad Dermatol Venereol. 2015 Jun;29(6):1245-7. doi: 10.1111/jdv.12703. Epub 2014 Sep 8.
7
Dramatic reduction of clindamycin plasma concentration in hidradenitis suppurativa patients treated with the rifampin-clindamycin combination.在接受利福平-克林霉素联合治疗的化脓性汗腺炎患者中，克林霉素血浆浓度显著降低。
Eur J Dermatol. 2014 Jan-Feb;24(1):94-5. doi: 10.1684/ejd.2013.2213.
8
γ-Secretase mutations in hidradenitis suppurativa: new insights into disease pathogenesis.γ-分泌酶突变与化脓性汗腺炎：对疾病发病机制的新认识。
J Invest Dermatol. 2013 Mar;133(3):601-607. doi: 10.1038/jid.2012.372. Epub 2012 Oct 25.
9
Incidence, mortality, and disease associations of pyoderma gangrenosum in the United Kingdom: a retrospective cohort study.英国坏疽性脓皮病的发病率、死亡率和疾病相关性：一项回顾性队列研究。
J Invest Dermatol. 2012 Sep;132(9):2166-70. doi: 10.1038/jid.2012.130. Epub 2012 Apr 26.
10
Considering hidradenitis suppurativa as a bacterial biofilm disease.将化脓性汗腺炎视为一种细菌生物膜疾病。
FEMS Immunol Med Microbiol. 2012 Jul;65(2):385-9. doi: 10.1111/j.1574-695X.2012.00946.x. Epub 2012 Mar 12.