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糖缀合物两亲分子化学的最新进展。

Recent Advances in the Chemistry of Glycoconjugate Amphiphiles.

机构信息

ARNA Laboratory, Inserm U1212, CNRS UMR 5320, Université de Bordeaux, F-33000 Bordeaux, France.

出版信息

Molecules. 2018 Jan 2;23(1):89. doi: 10.3390/molecules23010089.

DOI:10.3390/molecules23010089
PMID:29301326
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6017060/
Abstract

Glyconanoparticles essentially result from the (covalent or noncovalent) association of nanometer-scale objects with carbohydrates. Such glyconanoparticles can take many different forms and this mini review will focus only on soft materials (colloids, liposomes, gels etc.) with a special emphasis on glycolipid-derived nanomaterials and the chemistry involved for their synthesis. Also this contribution presents Low Molecular Weight Gels (LMWGs) stabilized by glycoconjugate amphiphiles. Such soft materials are likely to be of interest for different biomedical applications.

摘要

糖基纳米粒子主要是由纳米级物体与碳水化合物的（共价或非共价）结合而形成的。这些糖基纳米粒子可以有多种不同的形式，而本篇综述将仅关注软物质（胶体、脂质体、凝胶等），特别强调糖脂衍生的纳米材料及其合成所涉及的化学。本文还介绍了糖缀合物两亲分子稳定的低分子量凝胶（LMWGs）。这些软物质可能会在不同的生物医学应用中引起兴趣。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e31b/6017060/5224954de39e/molecules-23-00089-g005.jpg
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https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e31b/6017060/5224954de39e/molecules-23-00089-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e31b/6017060/ac06552b84c6/molecules-23-00089-sch001.jpg
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https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e31b/6017060/51ff23405c8b/molecules-23-00089-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e31b/6017060/81d744bb6385/molecules-23-00089-sch002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e31b/6017060/a7c4e3b5529d/molecules-23-00089-sch003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e31b/6017060/063c686efcc0/molecules-23-00089-sch004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e31b/6017060/ae3b2450735b/molecules-23-00089-sch005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e31b/6017060/2d96109a1c72/molecules-23-00089-sch006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e31b/6017060/e2009e83c912/molecules-23-00089-sch007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e31b/6017060/9394a517c0c6/molecules-23-00089-sch008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e31b/6017060/683a68ed33ff/molecules-23-00089-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e31b/6017060/3e844238bdb7/molecules-23-00089-sch009.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e31b/6017060/7c2597b9c36f/molecules-23-00089-sch010.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e31b/6017060/80648f11d551/molecules-23-00089-sch011.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e31b/6017060/faadf1fd74f9/molecules-23-00089-g004.jpg
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https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e31b/6017060/5224954de39e/molecules-23-00089-g005.jpg

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J Mater Chem B. 2016 Jun 21;4(23):4227-4233. doi: 10.1039/c6tb00344c. Epub 2016 May 31.
2
Carbamate-Based Bolaamphiphile as Low-Molecular-Weight Hydrogelators.基于氨基甲酸酯的双亲性分子作为低分子量水凝胶剂
Gels. 2016 Sep 28;2(4):25. doi: 10.3390/gels2040025.
3
Amphiphilic p-tert-Butylcalix[4]arene Scaffolds Containing Exposed Carbohydrate Dendrons.含有外露碳水化合物树枝状分子的两亲性对叔丁基杯[4]芳烃支架
基于环糊精的功能性糖纳米材料
Nanomaterials (Basel). 2020 Dec 15;10(12):2517. doi: 10.3390/nano10122517.
Angew Chem Int Ed Engl. 1999 Feb 1;38(3):369-372. doi: 10.1002/(SICI)1521-3773(19990201)38:3<369::AID-ANIE369>3.0.CO;2-1.
4
Polyvalent Interactions in Biological Systems: Implications for Design and Use of Multivalent Ligands and Inhibitors.生物系统中的多价相互作用：对多价配体和抑制剂设计与应用的启示
Angew Chem Int Ed Engl. 1998 Nov 2;37(20):2754-2794. doi: 10.1002/(SICI)1521-3773(19981102)37:20<2754::AID-ANIE2754>3.0.CO;2-3.
5
Biomedical applications of glyconanoparticles based on quantum dots.基于量子点的糖纳米粒子在生物医学中的应用。
Biochim Biophys Acta Gen Subj. 2018 Mar;1862(3):427-439. doi: 10.1016/j.bbagen.2017.11.010. Epub 2017 Nov 7.
6
Disassembly of Bacterial Biofilms by the Self-Assembled Glycolipids Derived from Renewable Resources.可再生资源衍生的自组装糖脂对细菌生物膜的瓦解作用。
ACS Appl Mater Interfaces. 2017 Nov 22;9(46):40047-40058. doi: 10.1021/acsami.7b12225. Epub 2017 Nov 10.
7
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Chemistry. 2018 Jan 19;24(4):762-776. doi: 10.1002/chem.201703374. Epub 2017 Oct 25.
8
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J Tissue Eng Regen Med. 2018 Mar;12(3):e1489-e1500. doi: 10.1002/term.2569. Epub 2017 Dec 10.
9
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Colloids Surf B Biointerfaces. 2017 Nov 1;159:605-612. doi: 10.1016/j.colsurfb.2017.08.016. Epub 2017 Aug 16.
10
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Biomaterials. 2017 Nov;145:72-80. doi: 10.1016/j.biomaterials.2017.08.034. Epub 2017 Aug 19.