Xu Yaqin, Deng Yunhua
Department of Dermatology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Facial Plast Surg. 2018 Apr;34(2):205-219. doi: 10.1055/s-0037-1606096. Epub 2018 Jan 5.
Ablative fractional carbon dioxide laser resurfacing is a well-established treatment for acne scars. However, there are limited consensus and guidelines regarding the procedure, such as its treatment plan, efficacy, and safety. In this study, we performed a systematic review to assess the efficacy and safety of the fractional carbon dioxide laser treatment procedure, and to provide evidence-based recommendations concerning its practical use on atrophic acne scars. A comprehensive search was performed in, EMBASE, Ovid, Web of Science, and Cochrane databases, using the keywords "scar(s)," "acne vulgaris," "carbon dioxide," and "fraction* laser(s)" for the period from January 1987 to December 2016. The initial literature search identified 337 articles. The final selection included 30 studies: 12 retrospective studies and 18 prospective randomized clinical trials. Ablative fractional carbon dioxide laser is an effective therapy for the treatment of acne scars. The treatment session, interval, and parameters should be customized for each patient. Combination therapy should be considered for ice-pick type acne scars. The use of dermocosmetics in pre- and postoperative care may be beneficial to patients.
剥脱性点阵二氧化碳激光换肤术是一种成熟的痤疮瘢痕治疗方法。然而，关于该手术的治疗方案、疗效和安全性等方面，共识和指南有限。在本研究中，我们进行了一项系统评价，以评估点阵二氧化碳激光治疗方法的疗效和安全性，并为其在萎缩性痤疮瘢痕的实际应用提供循证建议。我们使用关键词“瘢痕”“寻常痤疮”“二氧化碳”和“点阵*激光”，在1987年1月至2016年12月期间对EMBASE、Ovid、科学网和考克兰数据库进行了全面检索。初步文献检索共识别出337篇文章。最终纳入30项研究：12项回顾性研究和18项前瞻性随机临床试验。剥脱性点阵二氧化碳激光是治疗痤疮瘢痕的有效疗法。治疗疗程、间隔和参数应根据每位患者进行定制。对于冰锥型痤疮瘢痕，应考虑联合治疗。术前和术后护理中使用皮肤化妆品可能对患者有益。
