Department of Pharmacology, Catholic University of Health and Allied Sciences, Mwanza, Tanzania.
School of Pharmacy, Catholic University of Health and Allied Sciences, Mwanza, Tanzania.
BMC Pregnancy Childbirth. 2018 Jan 8;18(1):16. doi: 10.1186/s12884-017-1642-8.
Self-medication is a universal challenge that requires attention because of the potential threat not only to the pregnant women but also to unborn child. Data on self-medication practice and predictors among pregnant women is lacking in Tanzania. Information on the effects of this practice to the pregnant woman and the foetus globally is also scanty.
This was a cross sectional study which was conducted using face to face interview with 372 pregnant women at Makongoro health centre. Semi-structured questionnaires were used. Data were analysed using STATA 13 (Statistical Corporation, College Station, Texas, US).
A total of 372 pregnant women participated in the study. The prevalence of self-medication among pregnant women was 172 (46.24%). There was a significant statistical association between self-medication and occupation (P value =0.01), gestation age (P < 0.01) and education (P < 0.01). Age, marital status and gravidity were not associated with self-medication (P = 0.809, P = 0.243 and P = 0.922) respectively. When bivariate logistic regression was performed, occupation and education were the only determining factors for self-medication. Pregnant women who were unemployed, doing business and house wife were most likely to practice self-medication than employed pregnant women (P = 0.03; OR = 2.33; 95% CI, 1.06-5.31, P = 0.01; OR = 2.31; CI 1.21-4.41, P = <0.01, OR = 2.73, 95% CI 0.52-2.43) respectively. Pregnant women with no formal education, incomplete primary education, primary education and secondary education were most likely to practice self-medication than pregnant women with college or university education (P < 0.01, OR = 6.37 95% CI 2.37-19.03, P < 0.01, OR = 6.58, 95% CI 2.36-18.25, P < 0.01, OR = 3.78, 95% CI 1.89-7.56, P < 0.01, OR = 2.59 95% CI = 1.30-5.17). The leading illness/symptoms which led to self-medication among pregnant women attending clinic were malaria 56 (32.56%, morning sickness 44 (25.55%) and headache 33(19.19%). Drugs commonly used in self-medication among pregnant women were ant malarial 42 (24.42%), antiemetics 59 (34.30%) and analgesics 33 (19.19%).
Prevalence of self-medication among pregnant women is high in Tanzania. This is a threat to the safety of the developing foetus and the pregnant woman. Therefore there is a need of interventions to minimize the practice among pregnant women.
自我用药是一个普遍存在的挑战,需要引起关注,因为它不仅对孕妇,而且对未出生的孩子都存在潜在威胁。坦桑尼亚缺乏关于孕妇自我用药情况和预测因素的数据。全球范围内,关于这种做法对孕妇和胎儿的影响的信息也很少。
这是一项横断面研究,在 Makongoro 保健中心对 372 名孕妇进行面对面访谈。使用半结构式问卷进行调查。使用 STATA 13(Statistical Corporation,College Station,Texas,US)进行数据分析。
共有 372 名孕妇参加了这项研究。孕妇自我用药的患病率为 172 例(46.24%)。自我用药与职业(P 值=0.01)、妊娠龄(P<0.01)和教育程度(P<0.01)之间存在显著的统计学关联。年龄、婚姻状况和孕次与自我用药无关(P=0.809,P=0.243 和 P=0.922)。当进行二元逻辑回归分析时,职业和教育程度是自我用药的唯一决定因素。失业、经商和家庭主妇的孕妇比就业的孕妇更有可能自我用药(P=0.03;OR=2.33;95%CI,1.06-5.31,P=0.01;OR=2.31;CI 1.21-4.41,P<0.01;OR=2.73,95%CI 0.52-2.43)。没有正规教育、不完全小学教育、小学教育和中学教育的孕妇比有大学或以上教育程度的孕妇更有可能自我用药(P<0.01;OR=6.37;95%CI 2.37-19.03,P<0.01;OR=6.58;95%CI 2.36-18.25,P<0.01;OR=3.78;95%CI 1.89-7.56,P<0.01;OR=2.59;95%CI 1.30-5.17)。在就诊的孕妇中,导致自我用药的主要疾病/症状是疟疾 56 例(32.56%)、晨吐 44 例(25.55%)和头痛 33 例(19.19%)。孕妇自我用药中常用的药物是抗疟药 42 例(24.42%)、止吐药 59 例(34.30%)和镇痛药 33 例(19.19%)。
坦桑尼亚孕妇自我用药的患病率很高。这对未出生胎儿和孕妇的安全构成威胁。因此,有必要采取干预措施,尽量减少孕妇的这种做法。