Pagano Boza C, Vigo R, Premoli J E, Croxatto J, Gonzalez Barlatay J
a Department of Ophthalmology , Hospital Italiano de Buenos Aires , Buenos Aires , Argentina.
b Department of Ocular Oncology , Hospital Italiano de Buenos Aires , Buenos Aires , Argentina.
Orbit. 2018 Oct;37(5):389-392. doi: 10.1080/01676830.2017.1423353. Epub 2018 Jan 9.
Primary Apocrine adenocarcinomas (PAA) are very infrequent tumors that are often confused initially with benign lesions. Little is known about this disease and there is still much to be clarified. We present a case of PAA on the eyelid successfully treated with surgery alone and a literature review regarding what is currently described about this disease.
Noncomparative, retrospective case report of a patient with PAA on the eyelid succesfully treated with surgery alone and a literautre review.
A 91-year-old man with a 2 months lesion on the upper left eyelid was treated with surgery alone with oncological margins of 5mm. The Hystopathology diagnosis was a PAA of the eyelid and free margins were obtained. After 12 months of follow-up, the patient does not show any signs of local recurrence or distant metastasis. A review of the literature suggests these tumors are located more frequently in the axilla (50%) and secondly in the head and neck (35%), with similar distribution in the upper (41%) and lower eyelid (45%). The most commonly used treatment is surgical excision, but radiotherapy and chemotherapy have also been used with variable results.
PAA is a very rare and aggressive tumor. Because it is so infrequent, treatments are based on the sporadic cases encountered in the literature. As more cases are reported, more can be elucidated about the characteristics of this tumor, its behavior and best treatment choice and this may allow progress in the understanding and management of this disease.
原发性大汗腺癌（PAA）是非常罕见的肿瘤，最初常与良性病变混淆。关于这种疾病知之甚少，仍有许多需要阐明的地方。我们报告一例仅通过手术成功治疗的眼睑原发性大汗腺癌病例，并对目前关于该疾病的描述进行文献综述。
对一例仅通过手术成功治疗的眼睑原发性大汗腺癌患者进行非对照性回顾性病例报告，并进行文献综述。
一名91岁男性，左上眼睑有2个月的病变，仅接受了手术治疗，手术切缘为5mm。组织病理学诊断为眼睑原发性大汗腺癌，切缘阴性。随访12个月后，患者未出现任何局部复发或远处转移的迹象。文献综述表明，这些肿瘤更常见于腋窝（50%），其次是头颈部（35%），在上眼睑（41%）和下眼睑（45%）的分布相似。最常用的治疗方法是手术切除，但放疗和化疗也有应用，效果不一。
原发性大汗腺癌是一种非常罕见且侵袭性强的肿瘤。由于其非常罕见，治疗方法基于文献中报道的散发病例。随着更多病例的报告，可以更清楚地了解这种肿瘤的特征、行为和最佳治疗选择，这可能有助于在该疾病的理解和管理方面取得进展。
