National Diabetes, Obesity and Cholesterol Foundation, New Delhi, India.
Diabetes Foundation (India), New Delhi, India.
J Diabetes Res. 2017;2017:7254174. doi: 10.1155/2017/7254174. Epub 2017 Nov 29.
We studied the impact of the multicomponent interventions on body weight and cardiometabolic risk factors in overweight individuals working in corporate worksites.
Overweight (BMI ≥ 23 kg/m) subjects were recruited from four randomised worksites [two active intervention (, recruited, 180, completed 156) and two control (, recruited 130, completed 111)]. Intensive intervention was given at intervention worksite.
High prevalence (%) of obesity (90.9, 80.2), abdominal obesity (93.5, 84.3), excess skinfold thickness (70.3, 75.9), and low high-density lipoprotein cholesterol (HDL-c) levels (56.8, 63.7) were seen in the intervention and the control group, respectively. At the end of intervention, the following significant changes were observed in the intervention group: decrease in weight, BMI, waist circumference, serum triglycerides, and increase in HDL-c. Weight loss of more than 5% was seen in 12% and 4% individuals in the intervention and control groups, respectively. Most importantly, the sum of all the skinfold measurements (mm) in the intervention group decreased significantly more than the control group (12.51 ± 10.38 versus 3.50 ± 8.18, resp.).
This multicomponent worksite trial showed a reduction in weight, excess subcutaneous fat, and cardiometabolic risk factors after 6 months of active intervention in overweight Asian Indians.
This trial is registered with NCT03249610.
我们研究了多组分干预对超重个体在企业工作场所体重和心血管代谢危险因素的影响。
从四个随机工作场所招募超重（BMI≥23kg/m）受试者[两个主动干预（，招募，180，完成 156）和两个对照（，招募，130，完成 111）]。在干预工作场所进行强化干预。
干预组和对照组肥胖（90.9%，80.2%）、腹部肥胖（93.5%，84.3%）、多余皮褶厚度（70.3%，75.9%）和低高密度脂蛋白胆固醇（HDL-c）水平（56.8%，63.7%）的患病率较高。干预结束时，干预组体重、BMI、腰围、血清甘油三酯降低，HDL-c升高。干预组有 12%和对照组有 4%的个体体重减轻超过 5%。最重要的是，干预组所有皮褶测量值（mm）总和显著减少，比对照组多 12.51±10.38 对 3.50±8.18（分别）。
这项多组分工作场所试验表明，在超重的亚洲印度人中，经过 6 个月的积极干预，体重、过多的皮下脂肪和心血管代谢危险因素减少。
本试验在 NCT03249610 注册。
