Maiorana C, Pivetti L, Signorino F, Grossi G B, Herford A S, Beretta M
Oral Surgery, Center for Edentulism and Jaw Atrophies, Maxillofacial Surgery and Dentistry Unit, Fondazione IRCCS Cà Granda-Ospedale Maggiore Policlinico, University of Milan, Milan, Italy.
Center for Edentulism and Jaw Atrophies, Maxillofacial Surgery and Dentistry Unit, Fondazione IRCCS Cà Granda-Ospedale Maggiore Policlinico, University of Milan, Via della Commenda 10, 20122, Milan, Italy.
Int J Implant Dent. 2018 Jan 10;4(1):1. doi: 10.1186/s40729-017-0113-3.
When keratinized tissue width around dental implants is poorly represented, the clinician could resort to autogenous soft tissue grafting. Autogenous soft tissue grafting procedures are usually associated with a certain degree of morbidity. Collagen matrices could be used as an alternative to reduce morbidity and intra-operatory times. The aim of this study was to assess the efficacy of a xenogeneic collagen matrix as a substitute for soft tissue grafting around dental implants.
Fifteen consecutive patients underwent a vestibuloplasty and keratinized tissue reconstruction around dental implants, both in the mandible and the maxilla, with a porcine collagen matrix. The so obtained keratinized tissues were measured and evaluated after 6 months and 1, 4, and 5 years.
The average gain of keratinized tissue was 5.7 mm. After 6 months, it was observed a resorption of 37%, after 1 year 48%, and after 5 years 59%. The mean gain of keratinized tissue after 5 years was 2.4 mm. Hemostatic effect and post-operative pain were evaluated too. All subjects referred minimal pain with no bleeding. No adverse reaction nor infection was noted.
The present study showed the efficacy of a porcine collagen matrix in keratinized tissue augmentation. The possibility to use a soft tissue substitute is a great achievement as morbidity decreases and bigger areas can be treated in a single surgery.
当牙种植体周围角化组织宽度不足时，临床医生可采用自体软组织移植。自体软组织移植手术通常会伴随一定程度的发病率。胶原基质可作为一种替代方法，以降低发病率和手术时间。本研究的目的是评估异种胶原基质作为牙种植体周围软组织移植替代物的疗效。
连续15例患者在下颌骨和上颌骨的牙种植体周围进行前庭成形术和角化组织重建，使用猪胶原基质。在6个月、1年、4年和5年后对所获得的角化组织进行测量和评估。
角化组织的平均增加量为5.7毫米。6个月后，观察到吸收37%，1年后吸收48%，5年后吸收59%。5年后角化组织的平均增加量为2.4毫米。还评估了止血效果和术后疼痛。所有受试者均表示疼痛轻微且无出血。未观察到不良反应或感染。
本研究表明猪胶原基质在增加角化组织方面的疗效。使用软组织替代物的可能性是一项重大成就，因为发病率降低，且在一次手术中可治疗更大的面积。
