Biological Research Laboratory, Goiano Federal Institute-Urutá Campos, Urutá, GO, Brazil.
Post-Graduation Program in Cerrado Natural Resource Conservation and Biological Research Laboratory, Goiano Federal Institution-Urutaí Campus, Urutaí, GO, Brazil.
Environ Sci Pollut Res Int. 2018 Mar;25(9):8592-8607. doi: 10.1007/s11356-017-1150-4. Epub 2018 Jan 9.
Recent studies have shown that cigarette consumption affects much more than human health. Smoked cigarette butt (SCB) disposal into the environment can bring little-known negative biological consequences to mammals, since it contains many organic and inorganic toxic chemical constituents. Thus, we aim at assessing whether the ingestion of water with leached SCB for 60 days by female Swiss mice changes their defensive behavioral response to potential predators (cats and snakes). We worked with the following groups of animals: control (pollutant-free water), water with environmental concentration of SCB (1.9 μg/L of nicotine), and concentration 1000 times higher (EC1000×). Our data show that the treatments did not cause locomotor, visual, auditory, and olfactory deficit in the animals. However, we observed that the animals exposed to the pollutants did not present behavioral differences in the test session with or without the snake. On the other hand, animals in all groups showed defensive behavior when the test was conducted with the cat in the apparatus. However, female mice presented weaker response than the control. Thus, our data point towards the potential neurotoxic damage caused to mice who have ingested water with SCB residues, even at low concentrations.
最近的研究表明，吸烟不仅影响人类健康。将吸烟后的烟头（SCB）丢弃到环境中会给哺乳动物带来鲜为人知的负面生物后果，因为它含有许多有机和无机有毒化学成分。因此，我们旨在评估雌性瑞士小鼠连续 60 天摄入含有浸出 SCB 的水是否会改变它们对潜在捕食者（猫和蛇）的防御行为反应。我们使用了以下几组动物：对照组（无污染水）、含有环境浓度 SCB（1.9μg/L 尼古丁）的水组和浓度高 1000 倍的组（EC1000×）。我们的数据表明，这些处理没有导致动物出现运动、视觉、听觉和嗅觉缺陷。然而，我们观察到，暴露于污染物的动物在有或没有蛇的测试中没有表现出行为差异。另一方面，所有组的动物在有猫的设备测试中都表现出防御行为。然而，与对照组相比，雌性小鼠的反应较弱。因此，我们的数据表明，即使在低浓度下，摄入含有 SCB 残留物的水也会对小鼠造成潜在的神经毒性损伤。
