Costa Weruska Alcoforado, Monteiro Michelly Nóbrega, Queiroz Janice França, Gonçalves Ana Katherine
Universidade Federal do Rio Grande do Norte, Natal, RN, BR.
Clinics (Sao Paulo). 2017 Dec;72(12):758-763. doi: 10.6061/clinics/2017(12)07.
To evaluate the influence of pain on quality of life in breast cancer patients.
A cross-sectional study of 400 patients, including 118 without metastasis, 160 with loco-regional metastasis and 122 with distant metastasis. The instruments used were the European Organization for Research and Treatment for Cancer Quality of Life Questionnaire-Core 30 and the Breast Cancer-specific 23 and short McGill Pain Questionnaire.
In total, 71.7% of patients reported pain. The most frequent sensory descriptor used by patients was 'jumping.' In the evaluative dimension, the main descriptor chosen was troublesome. The Global Health self-assessment showed pain to be inversely correlated with quality of life: the group without metastasis had a mean score of 55.3 (SD=24.8) for those in pain, which rose to 69.7 (SD=19.2) for those without pain (p=0.001). Subjects with loco-regional metastasis had score of 59.1 (SD=21.3) when in pain, and those without pain had a significantly higher score of 72.4 (SD=18.6) (p<0.001). Patients from the distant metastasis group showed similar results with a mean score of 48.6 (SD=23.1) for those in pain and 67.6 (SD=20.4) for those without pain (p=0.002). Regarding the association of pain intensity and quality of life, patients with distant metastasis and intense pain had the worst scores for quality of life with a functional scale mean of 49.9 (SD=17.3) (p<0.009), a Symptom Scale score of 50.0 (SD=20.1) (p<0.001) and a Global Health Scale score of 39.7 (SD=24.7) (p<0.006).
Pain compromises the quality of life of patients with breast cancer, particularly those with advanced stages of the disease.
评估疼痛对乳腺癌患者生活质量的影响。
对400例患者进行横断面研究，其中118例无转移，160例有局部区域转移，122例有远处转移。使用的工具包括欧洲癌症研究与治疗组织生活质量问卷核心30项、乳腺癌特异性23项问卷和简短麦吉尔疼痛问卷。
总体而言，71.7%的患者报告有疼痛。患者最常使用的感觉描述词是“跳动”。在评价维度上，选择的主要描述词是“令人烦恼”。总体健康自我评估显示疼痛与生活质量呈负相关：无转移组中疼痛患者的平均得分为55.3（标准差=24.8），无疼痛患者的平均得分升至69.7（标准差=19.2）（p=0.001）。局部区域转移患者疼痛时的得分为59.1（标准差=21.3），无疼痛患者的得分显著更高，为72.4（标准差=18.6）（p<0.001）。远处转移组患者的结果相似，疼痛患者的平均得分为48.6（标准差=23.1），无疼痛患者的平均得分为67.6（标准差=20.4）（p=0.002）。关于疼痛强度与生活质量的关联，远处转移且疼痛剧烈的患者生活质量得分最差，功能量表平均得分为49.9（标准差=17.3）（p<0.009），症状量表得分为50.0（标准差=20.1）（p<0.001），总体健康量表得分为39.7（标准差=24.7）（p<0.006）。
疼痛会损害乳腺癌患者的生活质量，尤其是疾病晚期患者。
