Rzepakowska Anna, Sielska-Badurek Ewelina, Cruz Raul, Sobol Maria, Osuch-Wójcikiewicz Ewa, Niemczyk Kazimierz
Otolaryngology Department, Warsaw Medical University, Warsaw, Poland.
Otolaryngology Department, Kaiser Permanente Medical Center, Oakland, California.
Head Neck. 2018 May;40(5):927-936. doi: 10.1002/hed.25047. Epub 2018 Jan 10.
This is a comparative analysis of the diagnostic accuracy of narrow band imaging (NBI) and laryngovideostroboscopy (LVS) in the assessment of premalignant and malignant vocal fold lesions.
A prospective analysis was performed on 105 consecutive patients with vocal fold lesions. The NBI and LVS were obtained before the microsurgery.
The NBI and LVS showed no significant differences in identifying premalignant and malignant pathologies. However, in analysis restricted to identification of only malignant lesions, the specificity (88.9% vs 20.6%), accuracy (90.5% vs 51.4%), and positive predictive value (PPV; 84.8% vs 45.1%) were significantly higher for NBI (P value < .001; .015; and .045, respectively). A comparison of LVS scored results relative to each NBI type revealed statistically significant differences (P < .001). A moderate positive correlation between NBI and LVS was demonstrated (P = .54).
The NBI and LVS are useful, complementary tools in evaluating early potential vocal fold malignancies. The NBI was superior to LVS on several statistical analyses.
本研究旨在比较窄带成像（NBI）和喉镜频闪检查（LVS）在评估声带癌前病变和恶性病变时的诊断准确性。
对105例连续性声带病变患者进行前瞻性分析。在显微手术前进行NBI和LVS检查。
NBI和LVS在识别癌前病变和恶性病变方面无显著差异。然而，在仅针对恶性病变识别的分析中，NBI的特异性（88.9%对20.6%）、准确性（90.5%对51.4%）和阳性预测值（PPV；84.8%对45.1%）显著更高（P值分别<0.001、0.015和0.045）。LVS评分结果与每种NBI类型的比较显示出统计学显著差异（P<0.001）。NBI和LVS之间存在中度正相关（P = 0.54）。
NBI和LVS是评估早期潜在声带恶性肿瘤的有用的互补工具。在多项统计分析中，NBI优于LVS。
