大肠杆菌的phs位点，一种在代谢中引起多效性损伤的突变，是一种rpoA等位基因。
phs Locus of Escherichia coli, a mutation causing pleiotropic lesions in metabolism, is an rpoA allele.
作者信息
Rowland G C, Giffard P M, Booth I R
出版信息
J Bacteriol. 1985 Nov;164(2):972-5. doi: 10.1128/jb.164.2.972-975.1985.
Abstract
The phs mutation, which causes a pleiotropic growth defect, has been mapped and shown to be an allele of rpoA, the gene for the alpha subunit of RNA polymerase. The mutation is shown to cause a transcription defect in the arabinose operon, araBAD.
摘要
导致多效性生长缺陷的phs突变已被定位，并被证明是rpoA的一个等位基因，rpoA是RNA聚合酶α亚基的基因。该突变被证明会导致阿拉伯糖操纵子araBAD中的转录缺陷。
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本文引用的文献
1
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J Bacteriol. 1962 Jul;84(1):137-46. doi: 10.1128/jb.84.1.137-146.1962.
2
Nucleotide sequence of the rpoA-rplQ DNA of Escherichia coli: a second regulatory binding site for protein S4?大肠杆菌rpoA-rplQ DNA的核苷酸序列：蛋白质S4的第二个调节结合位点？
Nucleic Acids Res. 1984 Jul 25;12(14):5813-21. doi: 10.1093/nar/12.14.5813.
3
Genetic studies of the phs locus of Escherichia coli, a mutation causing pleiotropic lesions in metabolism and pH homeostasis.
FEBS Lett. 1984 Aug 6;173(2):295-300. doi: 10.1016/0014-5793(84)80794-2.
4
Linkage map of Escherichia coli K-12, edition 7.大肠杆菌K-12连锁图谱，第7版。
Microbiol Rev. 1983 Jun;47(2):180-230. doi: 10.1128/mr.47.2.180-230.1983.
5
Escherichia coli intracellular pH, membrane potential, and cell growth.大肠杆菌细胞内pH值、膜电位与细胞生长
J Bacteriol. 1984 Apr;158(1):246-52. doi: 10.1128/jb.158.1.246-252.1984.
6
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J Biol Chem. 1982 Apr 10;257(7):3687-91.
7
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Nucleic Acids Res. 1983 May 11;11(9):2599-616. doi: 10.1093/nar/11.9.2599.
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J Biol Chem. 1982 Apr 10;257(7):3692-6.
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Biochimie. 1985 Jan;67(1):83-9. doi: 10.1016/s0300-9084(85)80233-9.
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