Institut für Organische Chemie, Universität Regensburg , Universitätsstrasse 31, D-93053 Regensburg, Germany.
Org Lett. 2018 Feb 2;20(3):648-651. doi: 10.1021/acs.orglett.7b03790. Epub 2018 Jan 12.
A visible-light-induced photocatalytic method for the arylsulfonylation of heterocycles has been developed. The synthetic utility of this reaction is reflected by the direct use of commercially available sulfonyl chlorides and heterocycles under room temperature conditions. Complementarily, the photocatalytic arylation of heterocycles by sulfonyl chlorides via extrusion of SO is feasible at elevated temperature conditions, allowing switching between arylation or arylsulfonylation with excellent chemoselectivity.
可见光诱导的杂环芳基磺酰化反应已被开发出来。该反应的合成实用性体现在可直接使用商业可得的磺酰氯和杂环化合物，在室温条件下进行反应。此外，通过 SO 的挤出，磺酰氯对杂环化合物的光催化芳基化反应在高温条件下也是可行的，这使得在芳基化或芳基磺酰化之间进行转换成为可能，且具有极好的化学选择性。
