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肯尼亚普通儿科病房新生儿入院时脱水的患病率及管理——一项临床审计

The Prevalence and Management of Dehydration amongst Neonatal Admissions to General Paediatric Wards in Kenya-A Clinical Audit.

作者信息

Akech Samuel, Rotich Beatrice, Chepkirui Mercy, Ayieko Philip, Irimu Grace, English Mike

机构信息

Kenya Medical Research Institute, Wellcome Trust Research Programme, Nairobi, Kenya.

Department of Paediatrics and Child Health, College of Health Sciences, University of Nairobi, P.O. Box 19676-00202, Nairobi, Kenya.

出版信息

J Trop Pediatr. 2018 Dec 1;64(6):516-522. doi: 10.1093/tropej/fmx108.

Abstract

An audit of randomly selected case records of 810 patients admitted to 13 hospitals between December 2015 and November 2016 was done. Prevalence of dehydration was 19.7% (2293 of 11 636) [95% CI: 17.1-22.6%], range across hospitals was 9.4% to 27.0%. Most cases with dehydration were clinically diagnosed (82 of 153; 53.6%), followed by excessive weight loss (54 of 153; 35.3%) and abnormal urea/electrolytes/creatinine (23 of 153; 15.0%). Documentation of fluids prescribed was poor but, where data were available, Ringers lactate (30 of 153; 19.6%) and 10% dextrose (18 of 153; 11.8%) were mostly used. Only 17 of 153 (11.1%) children had bolus fluid prescription, and Ringer's lactate was most commonly used for bolus at a median volume per kilogram body weight of 20 ml/kg (interquartile range, 12-30 ml/kg). Neonatal dehydration is common, but current documentation may underestimate the burden. Heterogeneity in practice likely reflects the absence of guidelines that in turn reflects a lack of research informing practical treatment guidelines.

摘要

对2015年12月至2016年11月期间入住13家医院的810例患者的随机抽取病例记录进行了审计。脱水患病率为19.7%(11636例中的2293例)[95%置信区间:17.1 - 22.6%],各医院范围为9.4%至27.0%。大多数脱水病例通过临床诊断(153例中的82例;53.6%),其次是体重过度减轻(153例中的54例;35.3%)和尿素/电解质/肌酐异常(153例中的23例;15.0%)。所开液体的记录情况不佳,但在有数据的情况下,乳酸林格液(153例中的30例;19.6%)和10%葡萄糖(153例中的18例;11.8%)使用最为频繁。153名儿童中只有17名(11.1%)有推注液体处方,乳酸林格液最常用于推注,每千克体重的中位数体积为20 ml/kg(四分位间距,12 - 30 ml/kg)。新生儿脱水很常见,但目前的记录可能低估了负担。实践中的异质性可能反映出缺乏指南,而这又反映出缺乏为实际治疗指南提供信息的研究。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4ed2/6276025/bfc2e834e0fb/fmx108f1.jpg

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