Women's College Research Institute, Women's College Hospital, Suite 6326, 76 Grenville St, Toronto, Ontario, M5S 1B2, Canada.
Department of Medicine, University of Toronto, Toronto, ON, Canada.
Arthritis Res Ther. 2018 Jan 2;20(1):3. doi: 10.1186/s13075-017-1497-4.
There is limited information on the epidemiology of psoriatic arthritis (PsA) in general and in Middle Eastern populations in particular. The aims of this study were to estimate the prevalence and incidence rates of PsA and their temporal trends in the general population in Israel.
In this study, a cohort of adult patients with PsA was derived from the database of Clalit Health Services (CHS), Israel's largest health fund, with over 4.4 million members. The crude and age- and sex-standardized prevalence and incidence rates of PsA from 2006 to 2015 in the general population were calculated. The variation in PsA prevalence was assessed in relation to several demographic factors.
Among the 2,931,199 individuals aged 18 years and older registered in the CHS database in 2015, 4490 patients had a diagnosis of PsA (322 incident cases), resulting in overall crude prevalence and incidence rates of 0.153% (95% CI 0.149%, 0.158%) and 10.9 (95% CI 9.8, 12.3) per 100,000 population, respectively. The reported prevalence of PsA in Israel has doubled between 2006 and 2015 (from 0.073% to 0.153%). In contrast, the global incidence rate remained stable, with a gradual increase in incidence among individuals aged 51 to 70 years. PsA is associated with Jewish ethnicity, high socioeconomic status, and higher body mass index.
The prevalence and incidence of PsA in Israel are within the range of previous estimates from Southern European populations. An increase in the reported prevalence of PsA was observed over the past decade in the general population in Israel.
关于银屑病关节炎（PsA）的流行病学信息有限，特别是在中东人群中。本研究的目的是评估以色列普通人群中 PsA 的患病率和发病率及其时间趋势。
本研究从以色列最大的医疗保健基金 Clalit 健康服务（CHS）的数据库中提取了银屑病关节炎患者队列，该数据库拥有超过 440 万会员。计算了 2006 年至 2015 年普通人群中 PsA 的粗患病率和年龄及性别标准化患病率和发病率。评估了 PsA 患病率的变化与几个人口统计学因素的关系。
在 2015 年 CHS 数据库中登记的 2931199 名 18 岁及以上的个体中，有 4490 名患者被诊断为 PsA（322 例为新发病例），总粗患病率和发病率分别为 0.153%（95%CI 0.149%，0.158%）和 10.9（95%CI 9.8，12.3）/100000 人。2006 年至 2015 年期间，以色列报道的 PsA 患病率翻了一番（从 0.073%增加到 0.153%）。相比之下，全球发病率保持稳定，51 至 70 岁人群的发病率逐渐增加。PsA 与犹太种族、高社会经济地位和较高的体重指数有关。
以色列的 PsA 患病率和发病率在南欧人群的先前估计范围内。过去十年中，以色列普通人群中报告的 PsA 患病率有所增加。
