University of Toronto and Women's College Hospital, Toronto, Ontario, Canada.
University of Toronto and Institute for Clinical Evaluative Sciences, Toronto, Ontario, Canada.
Arthritis Care Res (Hoboken). 2019 Aug;71(8):1084-1091. doi: 10.1002/acr.23743. Epub 2019 Jul 11.
To estimate the prevalence and incidence of psoriasis and psoriatic arthritis (PsA) over time in Ontario, Canada.
We performed a population-based study of Ontario health administrative data, using validated case definitions for psoriasis and PsA. We computed the crude and age- and sex-standardized cumulative prevalence and incidence of psoriasis from 2000 to 2015.
Among the 10,774,802 individuals ages ≥20 years residing in Ontario in 2015, we identified 273,238 patients with psoriasis and 18,655 patients with PsA, equating to cumulative prevalence estimates of 2.54% and 0.17%, respectively. Correcting the prevalence estimates for imperfect sensitivity and specificity resulted in similar estimates. The male:female ratio was approximately 1.0 for both conditions. For psoriasis, the age- and sex-standardized cumulative prevalence increased from 1.74% in 2000 to 2.32% in 2015. For PsA, the age- and sex-standardized cumulative prevalence increased from 0.09% in 2008 to 0.15% in 2015. Between 2008 and 2015, annual incidence rates for psoriasis decreased, whereas those for PsA remained relatively stable.
The prevalence and incidence of psoriasis and PsA in Ontario are similar to those observed in Europe and the US. The steady increase in the prevalence of psoriasis and PsA over the past decade may be due to a combination of population aging, population growth, and increasing life expectancy.
评估加拿大安大略省银屑病和银屑病关节炎(PsA)的患病率和发病率随时间的变化趋势。
我们对安大略省的健康管理数据进行了一项基于人群的研究,使用经过验证的银屑病和 PsA 病例定义。我们计算了 2000 年至 2015 年期间银屑病的粗患病率和年龄及性别标准化累积患病率和发病率。
在 2015 年居住在安大略省的 10774802 名年龄≥20 岁的人群中,我们发现 273238 名银屑病患者和 18655 名 PsA 患者,相应的累积患病率估计值分别为 2.54%和 0.17%。对不完美的敏感性和特异性进行患病率校正后,得到了相似的估计值。两种疾病的男女比例均约为 1.0。对于银屑病,年龄及性别标准化累积患病率从 2000 年的 1.74%增加到 2015 年的 2.32%。对于 PsA,年龄及性别标准化累积患病率从 2008 年的 0.09%增加到 2015 年的 0.15%。在 2008 年至 2015 年期间,银屑病的年发病率下降,而 PsA 的发病率则相对稳定。
安大略省银屑病和 PsA 的患病率和发病率与欧洲和美国观察到的相似。过去十年中,银屑病和 PsA 的患病率稳步上升,可能是由于人口老龄化、人口增长和预期寿命延长的综合作用。