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角膜塑形术对近视屈光参差患者眼轴增长的影响。

Effects of orthokeratology on axial length growth in myopic anisometropes.

机构信息

Department of Ophthalmology and Vision Science, Eye and ENT Hospital, Fudan University, Shanghai, China; Key Laboratory of Myopia, Ministry of Health, China.

Department of Ophthalmology and Vision Science, Eye and ENT Hospital, Fudan University, Shanghai, China; Key Laboratory of Myopia, Ministry of Health, China.

出版信息

Cont Lens Anterior Eye. 2018 Jun;41(3):263-266. doi: 10.1016/j.clae.2017.10.014. Epub 2018 Jan 10.

Abstract

PURPOSE

To investigate the effect of orthokeratology (ortho-k) lens wear on axial length (AL) growth in juvenile myopic anisometropes.

METHODS

This retrospective study consisted of two parts. In Part One, 25 anisometropic participants (mean age, 11.2 ± 1.9 years; 11 females and 14 males) were fitted with ortho-k lenses in the more myopic eye only, and the rate of AL growth was compared between the ortho-k lens wearing eye and the untreated contralateral eye over an average period of 23.1 ± 8.3 months. In Part Two, 8 participants who developed myopia in the contralateral eye received ortho-k treatment in both eyes for an average of 12 months; the rate of AL growth before and after ortho-k treatment in the newly developed myopic eye was compared.

RESULTS

In Part One, the rate of AL elongation in the ortho-k treated eye (0.08 ± 0.15 mm/year) was significantly slower than in the contralateral eye (0.39 ± 0.32 mm/year) (P < 0.001). At the completion of Part One, 16 out of 25 participants (64%) developed myopia in the initially non-myopic eye. In Part Two, the rate of AL elongation after ortho-k treatment in the newly developed myopic eye (0.20 mm/year) was significantly slower than that before ortho-k treatment in the same eye (0.49 mm/year) (P = 0.012).

CONCLUSION

Ortho-k treatment slows AL growth in the more myopic eye of anisometropic patients; should the contralateral eye develop myopia in the future, ortho-k is capable of slowing down AL growth in that eye as well.

摘要

目的

研究角膜塑形术(ortho-k)镜片佩戴对青少年近视性屈光参差患者眼轴(axial length,AL)增长的影响。

方法

本回顾性研究分为两部分。在第一部分中,25 名屈光参差患者(平均年龄 11.2±1.9 岁;女性 11 名,男性 14 名)仅在近视程度较高的眼中佩戴 ortho-k 镜片,在平均 23.1±8.3 个月的时间内,比较佩戴 ortho-k 镜片眼和未经治疗的对侧眼的 AL 增长速度。在第二部分中,8 名患者对侧眼发生近视,双眼均接受 ortho-k 治疗 12 个月;比较新发生近视眼中 ortho-k 治疗前后的 AL 增长速度。

结果

在第一部分中,ortho-k 治疗眼(0.08±0.15mm/年)的 AL 伸长率明显慢于对侧眼(0.39±0.32mm/年)(P<0.001)。在第一部分结束时,25 名参与者中有 16 名(64%)最初非近视眼发展为近视。在第二部分中,新发生近视眼中 ortho-k 治疗后的 AL 伸长率(0.20mm/年)明显慢于同一眼中 ortho-k 治疗前的 AL 伸长率(0.49mm/年)(P=0.012)。

结论

ortho-k 治疗可减缓屈光参差患者近视眼中的 AL 增长;如果对侧眼将来发生近视,ortho-k 也能够减缓该眼中的 AL 增长。

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