Adekeye E O, Lavery K M
Br J Oral Maxillofac Surg. 1985 Dec;23(6):398-403. doi: 10.1016/0266-4356(85)90023-3.
A survey of cleft lip and palate in 160 Nigerians is presented. In clefts of the lip alone, there was no sex predilection whereas cleft lip and palate cases showed a slight male preponderance. 119 (74.4%) cases presented below the age of 12 years and 41 (25.6%) cases were first seen above 12 years of age. Only a few cleft lip and palate cases survived to adulthood possibly because of malnutrition combined with the lethal effects of associated congenital abnormalities. This study confirms the view that late primary repair of clefts is less likely to produce impaired growth of the maxilla due to contraction of scar tissue commonly seen in early surgery. The importance of early primary repair is emphasised.
本文介绍了对160名尼日利亚人唇腭裂情况的调查。仅唇裂病例中，不存在性别偏好，而唇腭裂病例则显示男性略占优势。119例（74.4%）病例在12岁以下出现，41例（25.6%）病例首次在12岁以上被发现。只有少数唇腭裂病例存活至成年，可能是由于营养不良以及相关先天性异常的致命影响。本研究证实了这样一种观点，即腭裂的晚期一期修复不太可能因早期手术中常见的瘢痕组织收缩而导致上颌骨生长受损。强调了早期一期修复的重要性。
