Woźniak Witold, Tarnas Monika, Miłek Tomasz, Mlosek Krzysztof R, Ciostek Piotr
First Department of General and Vascular Surgery, Second Faculty of Medicine with the English Division and the Physiotherapy Division, Medical University of Warsaw, Warsaw, Poland.
Microbiology Department, Mazovian Brodnowski Hospital in Warsaw, Warsaw, Poland.
Pol J Microbiol. 2016 Aug 26;65(3):353-357. doi: 10.5604/17331331.1215614.
Microbial colonisation of chronic venous ulcers and synergism between bacterial species slow down the healing process. The study aimed at performing qualitative analysis of microbial flora in venous leg ulcers treated with platelet rich plasma (PRP). Twenty two women and twelve men aged 47-90 years were treated with PRP at our department between 2012 and 2015. Ulcer cultures collected before and after PRP therapy yielded 83 and 110 microbial isolates, respectively, of Gram positive, Gram negative bacteria and candida. Pseudomonas aueruginosa and Staphylococcus aureus were the most common pre- and post-treatment isolates. PRP therapy and increased the variety of microbial flora.
慢性静脉溃疡的微生物定植以及细菌物种之间的协同作用会减缓愈合过程。本研究旨在对接受富血小板血浆(PRP)治疗的下肢静脉溃疡中的微生物菌群进行定性分析。2012年至2015年间,我们科室对22名年龄在47至90岁之间的女性和12名男性进行了PRP治疗。在PRP治疗前后采集的溃疡培养物分别产生了83株和110株革兰氏阳性菌、革兰氏阴性菌和念珠菌的微生物分离株。铜绿假单胞菌和金黄色葡萄球菌是治疗前和治疗后最常见的分离株。PRP治疗增加了微生物菌群的多样性。