党参水溶性提取物中二种脯氨酸型新儿茶素葡萄糖苷。
Two Novel Proline-Containing Catechin Glucoside from Water-Soluble Extract of Codonopsis pilosula.
机构信息
State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650201, China.
School of Pharmacy, Henan University of Chinese Medicine, Zhengzhou 450008, China.
出版信息
Molecules. 2018 Jan 16;23(1):180. doi: 10.3390/molecules23010180.
Choushenflavonoids A () and B (), two unusual proline-containing catechin glucosides, were isolated from the roots of cultivated in a high-altitude location of Yunnan province. Their structures were determined by spectroscopic data and chemical methods. Specifically, the absolute configuration of glucose residue in and was assigned by acid hydrolysis followed by derivatization and gas chromatography (GC) analysis. In addition, biological evaluation of and against Sirtuin 1 (SIRT1) was carried out.
从云南高海拔地区种植的 中分离得到两种罕见的含脯氨酸的儿茶素葡萄糖苷，即 Choushenflavonoids A () 和 B (). 通过光谱数据和化学方法确定了它们的结构。具体来说，通过酸水解、衍生化和气相色谱 (GC) 分析确定了 和 中葡萄糖残基的绝对构型。此外，还对 和 对 Sirtuin 1 (SIRT1) 的生物活性进行了评价。
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