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基于DNA的单分子电子学:从概念到功能

DNA-Based Single-Molecule Electronics: From Concept to Function.

作者信息

Wang Kun

机构信息

Department of Mechanical Engineering, University of Michigan, Ann Arbor, MI 48109, USA.

出版信息

J Funct Biomater. 2018 Jan 17;9(1):8. doi: 10.3390/jfb9010008.

Abstract

Beyond being the repository of genetic information, DNA is playing an increasingly important role as a building block for molecular electronics. Its inherent structural and molecular recognition properties render it a leading candidate for molecular electronics applications. The structural stability, diversity and programmability of DNA provide overwhelming freedom for the design and fabrication of molecular-scale devices. In the past two decades DNA has therefore attracted inordinate amounts of attention in molecular electronics. This review gives a brief survey of recent experimental progress in DNA-based single-molecule electronics with special focus on single-molecule conductance and characteristics of individual DNA molecules. Existing challenges and exciting future opportunities are also discussed.

摘要

除了作为遗传信息的储存库外,DNA作为分子电子学的构建模块正发挥着越来越重要的作用。其固有的结构和分子识别特性使其成为分子电子学应用的主要候选者。DNA的结构稳定性、多样性和可编程性为分子尺度器件的设计和制造提供了极大的自由度。因此,在过去二十年中,DNA在分子电子学领域引起了极大的关注。本文简要综述了基于DNA的单分子电子学的最新实验进展,特别关注单分子电导和单个DNA分子的特性。还讨论了现有的挑战和令人兴奋的未来机遇。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0948/5872094/d7c13a2ac5f6/jfb-09-00008-g001.jpg

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