a NU-Food Research Facility, Human Nutrition Research Centre, School of Agriculture, Food and Human Nutrition , Newcastle University , NE17RU Newcastle Upon-Tyne , UK.
b Wesnes Cognition Limited , Oxfordshire, England , UK.
Nutr Neurosci. 2019 Aug;22(8):596-606. doi: 10.1080/1028415X.2017.1420539. Epub 2018 Jan 17.
There is a growing body of evidence from randomized controlled trials which indicates that consumption of berries has a positive effect upon the cognitive function of healthy adults. It has been recommended that studies combining cognitive and physiological measures be undertaken in order to strengthen the evidence base for the putative effects of flavonoid consumption on cognitive outcomes. This pilot study utilized a randomized, double-blind and placebo controlled crossover design to assess the influence of the acute administration of anthocyanin-rich blackcurrant juice, standardized at 500 mg of polyphenols, on mood and attention. Additionally, this trial used electroencephalography (EEG) to assess if any changes in cognitive performance are associated with changes in localized prefrontal cortex neuronal activity in nine healthy young adults. Outcomes from the pilot EEG data highlight an anxiolytic effect of the consumption of a single serve blackcurrant juice, as indexed by a suppression of α spectral power, and an increase in the slow wave δ and θ spectral powers. There was also an indication of greater alertness and lower fatigue, as indexed by an increase in β power and suppression of α spectral power. Outcomes from the CogTrack™ system indicated a small acute increase in reaction times during the digit vigilance task.
越来越多的随机对照试验证据表明，食用浆果对健康成年人的认知功能有积极影响。有人建议进行结合认知和生理测量的研究，以加强黄酮类化合物摄入对认知结果的潜在影响的证据基础。这项初步研究采用随机、双盲和安慰剂对照交叉设计，评估了富含花青素的黑加仑汁（标准化为 500mg 多酚）的急性给药对情绪和注意力的影响。此外，该试验还使用脑电图（EEG）来评估在九名健康年轻成年人中，认知表现的任何变化是否与局部前额叶皮层神经元活动的变化相关。初步 EEG 数据的结果突出显示，单次黑加仑汁的摄入具有抗焦虑作用，这表现为α 频谱功率的抑制，以及慢波 δ 和θ 频谱功率的增加。β 功率的增加和α 频谱功率的抑制也表明警觉性更高，疲劳感更低。CogTrack™系统的结果表明，在数字警戒任务中，反应时间出现了短暂的急性增加。
