Graduate School of Nursing, Uniformed Services University of the Health Sciences, Bethesda, MD 20814, USA.
Department of Biomedical Engineering, George Washington University, Washington, DC 20052, USA.
Nutrients. 2023 Feb 27;15(5):1204. doi: 10.3390/nu15051204.
Optimal nutrition is imperative for psychological health. Oxidative stress and inflammation are underlying etiologies for alterations in psychological health. Warfighters are at risk of health concerns such as depression due to increased stress in austere environments and family separation while deployed. Over the last decade, research has demonstrated the health benefits of flavonoids found in fruits and berries. Berry flavonoids have potent antioxidant and anti-inflammatory properties by inhibiting oxidative stress and inflammation. In this review, the promising effects of various berries rich in bioactive flavonoids are examined. By inhibiting oxidative stress, berry flavonoids have the potential to modulate brain, cardiovascular, and intestinal health. There is a critical need for targeted interventions to address psychological health concerns within the warfighter population, and a berry flavonoid-rich diet and/or berry flavonoid dietary supplement intervention may prove beneficial as an adjunctive therapy. Structured searches of the literature were performed in the PubMed, CINAHL, and EMBASE databases using predetermined keywords. This review focuses on berry flavonoids' critical and fundamental bioactive properties and their potential effects on psychological health in investigations utilizing cell, animal, and human model systems.
最佳营养对于心理健康至关重要。氧化应激和炎症是心理 健康改变的潜在病因。由于在恶劣环境和部署期间与家人分离而增加的压力，作战人员面临着抑郁等健康问题的风险。在过去的十年中，研究已经证明了水果和浆果中发现的类黄酮对健康的益处。浆果类黄酮通过抑制氧化应激和炎症具有强大的抗氧化和抗炎特性。在这篇综述中，研究了富含生物活性类黄酮的各种浆果的有希望的作用。通过抑制氧化应激，浆果类黄酮有可能调节大脑、心血管和肠道健康。迫切需要针对作战人员群体的心理健康问题进行有针对性的干预，富含浆果类黄酮的饮食和/或浆果类黄酮膳食补充剂干预可能作为辅助治疗有益。在 PubMed、CINAHL 和 EMBASE 数据库中使用预定的关键词进行了文献的结构化搜索。本综述重点介绍了浆果类黄酮的关键和基本生物活性特性，以及它们在利用细胞、动物和人类模型系统进行的调查中对心理健康的潜在影响。
