Picone Pasquale, Girgenti Antonella, Buttacavoli Miriam, Nuzzo Domenico
Institute for Biomedical Research and Innovation, National Research Council of Italy, Palermo, Italy.
Department of Biomedicine, Neuroscience and Advanced Diagnostics (Bi.N.D), University of Palermo, Palermo, Italy.
Front Nutr. 2024 Nov 27;11:1489489. doi: 10.3389/fnut.2024.1489489. eCollection 2024.
The increasing prevalence of neurodegenerative disorders represents a challenge to the global health of all nations and populations, particularly with increasing longevity. Urgent prevention strategies are therefore needed, and one opportunity may be to explore the relationship between dietary patterns and brain health which has emerged as a promising strategy. Numerous studies indicate that dietary choices have a significant impact on cognitive function, memory and the risks of neurological disorders, recognizing the dynamic role of diet in maintaining cognitive abilities. One of the most studied dietary styles, the Mediterranean diet, characterized by healthy, plant-based foods fats and moderate consumption of animal products, has demonstrated its neuroprotective potential. Rich in antioxidants, vitamins and polyphenols, this diet shows consistent associations with cardiovascular health and cognitive function. Some less talked about foods, such as seaweed, blackcurrants, Lion's Mane mushroom and chia seeds, are emerging as potential brain health boosters. These and other new foods could enrich the Western diet making it capable of effectively preventing neurological disorders. Despite promising scientific data, difficulties persist in understanding the complex relationship between nutrition and brain health. Individual variability, long-term dietary adherence, comorbidities, and the need for rigorous clinical evidence pose obstacles. In this review, we would like to focus our attention on the future of brain-diets, which should involve accessible, personalized and evidence-based interventions, providing hope against the challenges posed by neurodegenerative diseases. In fact, as research progresses, more and more attention are being placed to brain health, promising a harmonious and resilient cognitive landscape for individuals and society.
神经退行性疾病患病率的不断上升对所有国家和人群的全球健康构成了挑战,尤其是在寿命不断延长的情况下。因此,迫切需要预防策略,一个机会可能是探索饮食模式与大脑健康之间的关系,这已成为一种有前景的策略。大量研究表明,饮食选择对认知功能、记忆力和神经疾病风险有重大影响,认识到饮食在维持认知能力方面的动态作用。研究最多的饮食方式之一——地中海饮食,其特点是食用健康的植物性食物脂肪和适量的动物产品,已显示出其神经保护潜力。这种饮食富含抗氧化剂、维生素和多酚,与心血管健康和认知功能始终存在关联。一些较少被提及的食物,如海藻、黑加仑、猴头菇和奇亚籽,正成为潜在的大脑健康促进剂。这些以及其他新食物可以丰富西方饮食,使其能够有效预防神经疾病。尽管有前景良好的科学数据,但在理解营养与大脑健康之间的复杂关系方面仍存在困难。个体差异、长期饮食依从性、合并症以及对严格临床证据的需求构成了障碍。在这篇综述中,我们希望将注意力集中在大脑饮食的未来,这应该包括可及的、个性化的和基于证据的干预措施,为应对神经退行性疾病带来的挑战带来希望。事实上,随着研究的进展,越来越多的注意力被放在大脑健康上,为个人和社会带来一个和谐且有恢复力的认知前景。