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干扰素-γ与结直肠癌:最新进展

Interferon-γ and Colorectal Cancer: an up-to date.

作者信息

Kosmidis Christoforos, Sapalidis Konstantinos, Koletsa Triantafyllia, Kosmidou Maria, Efthimiadis Christoforos, Anthimidis George, Varsamis Nikolaos, Michalopoulos Nikolaos, Koulouris Charilaos, Atmatzidis Stefanos, Liavas Lazaros, Strati Titika-Marina, Koimtzis Georgios, Tsakalidis Alexandros, Mantalovas Stylianos, Zarampouka Katerina, Florou Maria, Giannakidis Dimitrios E, Georgakoudi Eleni, Baka Sofia, Zarogoulidis Paul, Man Yan-Gao, Kesisoglou Isaac

机构信息

3rd Department of Surgery, AHEPA University Hospital, Aristotle University of Thessaloniki, Medical School.

Pathology Department, Faculty of Medicine, Aristotle University of Thessaloniki, Thessaloniki, Greece.

出版信息

J Cancer. 2018 Jan 1;9(2):232-238. doi: 10.7150/jca.22962. eCollection 2018.

DOI:10.7150/jca.22962
PMID:29344268
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5771329/
Abstract

Colorectal cancer still remains the third cause of cancer death among cancer patients. Early diagnosis is crucial and they can be either endoscopic or with blood biomarkers. Endoscopic methods consist of gastroscopy and colonoscopy, however; in recent years, endoscopic ultrasound is being used. The microenvironment is very important for the successful delivery of the treatment. Several proteins and hormones play a crucial role in the efficiency of the treatment. In the current mini review we will focus on interferon-γ.

摘要

结直肠癌仍然是癌症患者中癌症死亡的第三大原因。早期诊断至关重要,诊断方法可以是内镜检查或使用血液生物标志物。内镜检查方法包括胃镜检查和结肠镜检查;然而,近年来,内镜超声也被应用。微环境对于治疗的成功实施非常重要。几种蛋白质和激素在治疗效果中起着关键作用。在当前的小型综述中,我们将重点关注γ干扰素。

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Anticancer Res. 2017 Sep;37(9):4759-4766. doi: 10.21873/anticanres.11882.
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Specific Expression of Interferon-γ Induced by Synergistic Activation Mediator-Derived Systems Activates Innate Immunity and Inhibits Tumorigenesis.
白细胞介素(细胞因子)作为结直肠癌的生物标志物:进展、检测与监测
J Clin Med. 2023 Apr 25;12(9):3127. doi: 10.3390/jcm12093127.
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Unraveling the Complex Interconnection between Specific Inflammatory Signaling Pathways and Mechanisms Involved in HIV-Associated Colorectal Oncogenesis.解析特定炎症信号通路与HIV相关结直肠癌发生机制之间的复杂相互联系。
Cancers (Basel). 2023 Jan 25;15(3):748. doi: 10.3390/cancers15030748.
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