Asif Nayyab, Iqbal Razia, Nazir Chaudhry Fahad
Department of Zoology, University of Gujrat, Hafiz Hayat CampusGujrat, Pakistan.
Am J Clin Exp Immunol. 2017 Dec 20;6(6):92-96. eCollection 2017.
A joint function of tissues, organs and cells for the protection of body develops immune system. The human immune response against various infections during sleep, its mechanism, neuroimmune interactions, immunoregulatory effect of sleep along with sleep deprivation and role of cytokines in sleep deprivation were addressed. It is revealed that human immune system and sleep both are associated and influenced by each other. Sleep deprivation makes a living body susceptible to many infectious agents. In the result, immune system of human body is altered by releasing immunomodulators in the response of infections as reported by various researchers. Basic reasons and mechanisms of most of the poor sleep networks and release of proinflammatory modulators are still uncertain. The current situation requires improved sleep habits to make immune system efficient for a healthy life.
组织、器官和细胞共同发挥保护身体的功能,从而形成免疫系统。文中探讨了人类在睡眠期间针对各种感染的免疫反应、其机制、神经免疫相互作用、睡眠的免疫调节作用以及睡眠剥夺的影响,还有细胞因子在睡眠剥夺中的作用。研究表明,人类免疫系统与睡眠相互关联且相互影响。睡眠剥夺会使生物体易受多种感染因子的侵害。结果,正如众多研究人员所报告的那样,人体免疫系统会在感染反应中通过释放免疫调节剂而发生改变。大多数睡眠不佳网络以及促炎调节剂释放的基本原因和机制仍不确定。当前形势要求改善睡眠习惯,以使免疫系统高效运转,从而实现健康生活。