Valente P T, Atkinson B F, Guerry D
Acta Cytol. 1985 Nov-Dec;29(6):1026-8.
The urinary cytologic findings in a patient with metastatic malignant melanoma, diffuse melanosis and melanuria are presented. The melanosis was diagnosed from the clinical appearance of a generalized slate-blue skin discoloration, which is probably caused by dermal deposition of excess melanin pigment. The melanuria was characterized microscopically by the presence of amorphous, dark-brown casts, which stained positively for melanin pigment, and numerous pigment-laden macrophages.
本文报告了一名转移性恶性黑色素瘤、弥漫性黑变病和黑尿患者的尿细胞学检查结果。黑变病是根据全身石板蓝色皮肤变色的临床表现诊断的，这可能是由于过量黑色素在真皮沉积所致。黑尿在显微镜下的特征是存在无定形的深褐色管型，其黑色素染色呈阳性，以及大量含色素的巨噬细胞。
