Dairy Microbiology Division, ICAR-National Dairy Research Institute, Karnal, Haryana, -132001, India.
School of Biotechnology and Food Engineering, Department of Food Science and Engineering, Hefei University, Hefei City, Anhui Province, China.
Appl Microbiol Biotechnol. 2018 Feb;102(4):1599-1615. doi: 10.1007/s00253-018-8743-9. Epub 2018 Jan 19.
Foodstuffs and water are the key sources of cadmium biomagnifiaction. The available strategies to mitigate this problem are unproductive and expensive for practical large-scale use. Biological decontamination of metals through environmental microbes has been known since long time, whereas lactic acid bacteria (LAB) have not been extensively studied for this purpose. The LAB are known for maintaining homeostasis and suppression of pathogens in humans and animals. They also play a vital role in bioremediation of certain heavy metals. Recently in-vivo research findings strongly complement the in-vitro results in relation to decreased total body cadmium burden in animal model. This review summarizes the currently available information on impact of toxic metal (Cd) on human and animal health as well as cadmium sequestration through microbes placed broadly, whereas preeminent attention grabbed on LAB-cadmium interaction to explore their possible role in bioremediation of cadmium from foods and environment to safeguard human as well as environment health.
食品和水是镉生物放大的关键来源。目前用于缓解这一问题的策略在实际大规模应用中既没有成效又代价高昂。通过环境微生物进行金属的生物净化早已为人所知，而乳酸杆菌（LAB）在这方面的研究还不够广泛。LAB 以维持人类和动物体内的体内平衡和抑制病原体而闻名。它们在某些重金属的生物修复中也起着至关重要的作用。最近的体内研究结果有力地补充了体外研究结果，表明动物模型中总镉负荷降低。本文综述了目前关于有毒金属（Cd）对人类和动物健康的影响以及通过微生物广泛进行的镉固定的信息，而 LAB-镉相互作用引起了人们的极大关注，以探索它们在从食品和环境中生物修复镉以保护人类和环境健康方面的可能作用。
