• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

利用牛蒡根的功效：其药理特性与治疗应用综述

Harnessing the power of Arctium lappa root: a review of its pharmacological properties and therapeutic applications.

作者信息

Shyam Mukul, Sabina Evan Prince

机构信息

Department of Biotechnology, School of Biosciences and Technology, VIT University, SBST, VIT, Vellore, 632014, Tamil Nadu, India.

出版信息

Nat Prod Bioprospect. 2024 Aug 20;14(1):49. doi: 10.1007/s13659-024-00466-8.

DOI:10.1007/s13659-024-00466-8
PMID:39162715
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11335715/
Abstract

Arctium lappa, widely recognized as burdock, is a perennial plant that is employed in the realm of traditional Chinese medicine for a wide range of medicinal applications. The herb is rich in bioactive metabolites with therapeutic potential, encompassing polyphenolic antioxidants in its leaves, and flavonoids and fructo-oligosaccharides in its underground parts. Nutraceuticals originating from botanical sources such as Arctium lappa provide supplementary health advantages alongside their nutritional content and have demonstrated effectiveness in the prevention and management of specific ailments. The utilization of Arctium lappa root extract has exhibited encouraging outcomes in addressing hepatotoxicity induced by cadmium, lead, chromium, and acetaminophen, ameliorating liver damage and oxidative stress. Additionally, the root extract displays properties such as antidiabetic, hypolipidemic, aphrodisiac, anti-rheumatic, anti-Alzheimer, and various other pharmacological actions.

摘要

牛蒡，被广泛认为是牛蒡属植物，是一种多年生植物，在中国传统医学领域有广泛的药用应用。这种草药富含具有治疗潜力的生物活性代谢物，其叶子中含有多酚类抗氧化剂，地下部分含有黄酮类化合物和低聚果糖。源自牛蒡等植物来源的营养保健品除了其营养成分外，还提供补充健康益处，并已证明在预防和管理特定疾病方面有效。牛蒡根提取物在解决由镉、铅、铬和对乙酰氨基酚引起的肝毒性、改善肝损伤和氧化应激方面已显示出令人鼓舞的结果。此外，根提取物还具有抗糖尿病、降血脂、壮阳、抗风湿、抗阿尔茨海默病等多种药理作用。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/603a/11335715/901a91a58db9/13659_2024_466_Fig13_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/603a/11335715/42c940504d0c/13659_2024_466_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/603a/11335715/d17599b0a070/13659_2024_466_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/603a/11335715/5643949429db/13659_2024_466_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/603a/11335715/d85c6469e85d/13659_2024_466_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/603a/11335715/024fecc4d210/13659_2024_466_Fig5_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/603a/11335715/eb8f8b009188/13659_2024_466_Fig6_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/603a/11335715/66fdb847bc53/13659_2024_466_Fig7_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/603a/11335715/5dd36b39f92c/13659_2024_466_Fig8_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/603a/11335715/d99fb80196ec/13659_2024_466_Fig9_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/603a/11335715/b8e4ef62252f/13659_2024_466_Fig10_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/603a/11335715/2997eb09a6be/13659_2024_466_Fig11_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/603a/11335715/187afade2f38/13659_2024_466_Fig12_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/603a/11335715/901a91a58db9/13659_2024_466_Fig13_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/603a/11335715/42c940504d0c/13659_2024_466_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/603a/11335715/d17599b0a070/13659_2024_466_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/603a/11335715/5643949429db/13659_2024_466_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/603a/11335715/d85c6469e85d/13659_2024_466_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/603a/11335715/024fecc4d210/13659_2024_466_Fig5_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/603a/11335715/eb8f8b009188/13659_2024_466_Fig6_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/603a/11335715/66fdb847bc53/13659_2024_466_Fig7_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/603a/11335715/5dd36b39f92c/13659_2024_466_Fig8_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/603a/11335715/d99fb80196ec/13659_2024_466_Fig9_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/603a/11335715/b8e4ef62252f/13659_2024_466_Fig10_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/603a/11335715/2997eb09a6be/13659_2024_466_Fig11_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/603a/11335715/187afade2f38/13659_2024_466_Fig12_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/603a/11335715/901a91a58db9/13659_2024_466_Fig13_HTML.jpg

相似文献

1
Harnessing the power of Arctium lappa root: a review of its pharmacological properties and therapeutic applications.利用牛蒡根的功效：其药理特性与治疗应用综述
Nat Prod Bioprospect. 2024 Aug 20;14(1):49. doi: 10.1007/s13659-024-00466-8.
2
Arctium lappa (Burdock): Insights from ethnopharmacology potential, chemical constituents, clinical studies, pharmacological utility and nanomedicine.牛蒡（Arctium lappa）：从民族药理学潜力、化学组成、临床研究、药理学用途和纳米医学角度的深入了解。
Biomed Pharmacother. 2023 Feb;158:114104. doi: 10.1016/j.biopha.2022.114104. Epub 2022 Dec 12.
3
A review of the pharmacological effects of Arctium lappa (burdock).牛蒡的药理作用研究述评。
Inflammopharmacology. 2011 Oct;19(5):245-54. doi: 10.1007/s10787-010-0062-4. Epub 2010 Oct 28.
4
Aqueous extract of Arctium lappa L. root (burdock) enhances chondrogenesis in human bone marrow-derived mesenchymal stem cells.牛蒡根水提物增强人骨髓间充质干细胞的软骨分化。
BMC Complement Med Ther. 2020 Nov 23;20(1):364. doi: 10.1186/s12906-020-03158-1.
5
Ameliorative Effect of Arctium lappa Against Cadmium Genotoxicity and Histopathology in Kidney of Wistar Rat.牛蒡对Wistar大鼠肾脏镉遗传毒性和组织病理学的改善作用。
Pak J Biol Sci. 2017;20(6):314-319. doi: 10.3923/pjbs.2017.314.319.
6
Burdock (Arctium lappa L.) root attenuates preneoplastic lesion development in a diet and thioacetamide-induced model of steatohepatitis-associated hepatocarcinogenesis.牛蒡根可减轻饮食和硫代乙酰胺诱导的脂肪性肝炎相关肝癌发生模型中原发性病变的发展。
Environ Toxicol. 2020 Apr;35(4):518-527. doi: 10.1002/tox.22887. Epub 2019 Dec 5.
7
Ethanolic extract of root from Arctium lappa L ameliorates obesity and hepatic steatosis in rats by regulating the AMPK/ACC/CPT-1 pathway.牛蒡根乙醇提取物通过调节AMPK/ACC/CPT-1信号通路改善大鼠肥胖和肝脂肪变性。
J Food Biochem. 2022 Dec;46(12):e14455. doi: 10.1111/jfbc.14455. Epub 2022 Oct 1.
8
Phytochemicals and Biological Activities of Burdock (Arctium lappa L.) Extracts: A Review.牛蒡（Arctium lappa L.）提取物的植物化学物质和生物活性：综述。
Chem Biodivers. 2022 Nov;19(11):e202200615. doi: 10.1002/cbdv.202200615. Epub 2022 Nov 3.
9
Use of Arctium lappa Extract Against Acetaminophen-Induced Hepatotoxicity in Rats.牛蒡提取物对乙酰氨基酚诱导的大鼠肝毒性的作用
Curr Ther Res Clin Exp. 2015 May 27;77:73-8. doi: 10.1016/j.curtheres.2015.05.001. eCollection 2015 Dec.
10
Effect of aqueous extract of Arctium lappa L. (burdock) roots on the sexual behavior of male rats.牛蒡根水提取物对雄性大鼠性行为的影响。
BMC Complement Altern Med. 2012 Feb 1;12:8. doi: 10.1186/1472-6882-12-8.

引用本文的文献

1
Whole genome sequencing data of greater burdock () naturalized in the United States of America.在美利坚合众国归化的牛蒡全基因组测序数据。
Data Brief. 2025 Mar 21;60:111508. doi: 10.1016/j.dib.2025.111508. eCollection 2025 Jun.
2
Diabetic retinopathy: a comprehensive review of pathophysiology and emerging treatments.糖尿病视网膜病变：病理生理学与新兴治疗方法的全面综述
Mol Biol Rep. 2025 Apr 10;52(1):380. doi: 10.1007/s11033-025-10490-7.
3
The Role of Dietary Ingredients and Herbs in the Prevention of Non-Communicable Chronic Liver Disease.

本文引用的文献

1
L. roots inhibit the intestinal inflammation of dietary obese rats through TLR4/NF-κB pathway.L.根通过TLR4/NF-κB途径抑制饮食性肥胖大鼠的肠道炎症。
Heliyon. 2023 Nov 4;9(11):e21562. doi: 10.1016/j.heliyon.2023.e21562. eCollection 2023 Nov.
2
The protective effect of apigenin against inorganic arsenic salt-induced toxicity in PC12 cells.芹菜素对无机砷盐诱导的PC12细胞毒性的保护作用。
Environ Sci Pollut Res Int. 2023 Oct;30(48):106625-106635. doi: 10.1007/s11356-023-29884-w. Epub 2023 Sep 21.
3
Inulin ameliorates metabolic syndrome in high-fat diet-fed mice by regulating gut microbiota and bile acid excretion.
膳食成分和草药在预防非传染性慢性肝病中的作用。
Nutrients. 2024 Oct 16;16(20):3505. doi: 10.3390/nu16203505.
菊粉通过调节肠道微生物群和胆汁酸排泄改善高脂饮食喂养小鼠的代谢综合征。
Front Pharmacol. 2023 Jul 24;14:1226448. doi: 10.3389/fphar.2023.1226448. eCollection 2023.
4
The effects of hesperidin supplementation on cardiovascular risk factors in adults: a systematic review and dose-response meta-analysis.橙皮苷补充剂对成年人心血管危险因素的影响：一项系统评价与剂量反应荟萃分析。
Front Nutr. 2023 Jul 12;10:1177708. doi: 10.3389/fnut.2023.1177708. eCollection 2023.
5
Exploring the Mechanism of Arctium Lappa L. Leaves in the Treatment of Alzheimer's Disease Based on Chemical Profile, Network Pharmacology and Molecular Docking.基于化学特征、网络药理学和分子对接探究牛蒡叶治疗阿尔茨海默病的作用机制。
Adv Biol (Weinh). 2023 Aug;7(8):e2300084. doi: 10.1002/adbi.202300084. Epub 2023 Jun 29.
6
Diabetes, Cognition, and Mortality.糖尿病、认知与死亡率。
Am J Geriatr Psychiatry. 2023 Aug;31(8):583-585. doi: 10.1016/j.jagp.2023.05.003. Epub 2023 May 11.
7
Apigenin alleviates oxidative stress-induced myocardial injury by regulating SIRT1 signaling pathway.芹菜素通过调节SIRT1信号通路减轻氧化应激诱导的心肌损伤。
Eur J Pharmacol. 2023 Apr 5;944:175584. doi: 10.1016/j.ejphar.2023.175584. Epub 2023 Feb 11.
8
Lappaol F regulates the cell cycle by activating CDKN1C/p57 in human colorectal cancer cells.拉帕醇 F 通过激活人结直肠癌细胞中的 CDKN1C/p57 来调节细胞周期。
Pharm Biol. 2023 Dec;61(1):337-344. doi: 10.1080/13880209.2023.2172048.
9
Towards a better understanding of diabetes mellitus using organoid models.利用类器官模型深入了解糖尿病。
Nat Rev Endocrinol. 2023 Apr;19(4):232-248. doi: 10.1038/s41574-022-00797-x. Epub 2023 Jan 20.
10
Caffeic Acid and Diseases-Mechanisms of Action.咖啡酸与疾病-作用机制。
Int J Mol Sci. 2022 Dec 29;24(1):588. doi: 10.3390/ijms24010588.