Eid Ahmad M, Elmarzugi Nagib A, Abu Ayyash Laila M, Sawafta Maher N, Daana Hadeel I
Department of Pharmacy, Faculty of Medicine and Health Sciences, An-Najah National University, Nablus, State of Palestine.
Department of Industrial Pharmacy, Faculty of Pharmacy, Tripoli University & National Nanotechnology Project, Biotechnology Research Center, Tripoli, Libya.
J Trop Med. 2017;2017:7092514. doi: 10.1155/2017/7092514. Epub 2017 Nov 22.
It is estimated by the World Health Organization (WHO) that most of the world's population depends on herbal medicine for their health care. also known as black-caraway and as "Kalonji," is a well-known seed all over the world. It is one of the most common medicinal plants worldwide and contains many useful chemical constituents that we can find in its fixed oil, such as thymoquinone, thymohydroquinone, dithymoquinone, thymol, nigellicine, carvacrol, nigellimine, nigellicine, nigellidine, and alpha-hederin. Due to these numerous important ingredients it was found that it affects different areas of our body and has many pharmacological effects as antibacterial, antiviral, anti-inflammatory, and wound healing effect and also for acne vulgaris, skin cancer, pigmentation, and many cosmeceutical applications. Based on the folklore usage of seeds and oil, they are used in various systems of food and medicines. The aim of this article is to provide a detailed survey of the literature of cosmeceutical and external applications of which is expected to stimulate further studies on this subject.
世界卫生组织（WHO）估计，世界上大多数人口依靠草药进行医疗保健。它也被称为黑孜然和“卡隆吉”，是一种在世界各地都很知名的种子。它是全球最常见的药用植物之一，其固定油中含有许多有用的化学成分，如百里醌、百里氢醌、二百里醌、百里酚、黑种草碱、香芹酚、黑种草胺、黑种草碱、黑种草定和α-常春藤皂苷元。由于这些众多重要成分，人们发现它会影响我们身体的不同部位，并具有许多药理作用，如抗菌、抗病毒、抗炎和伤口愈合作用，还可用于寻常痤疮、皮肤癌、色素沉着以及许多美容应用。基于种子和油的民间用法，它们被用于各种食品和医药体系。本文的目的是对黑种草的美容及外用文献进行详细综述，预计这将激发对该主题的进一步研究。
