Glaser R, Kiecolt-Glaser J K, Stout J C, Tarr K L, Speicher C E, Holliday J E
Psychiatry Res. 1985 Nov;16(3):233-9. doi: 10.1016/0165-1781(85)90111-8.
The percentages of total T-lymphocytes (OKT-3+), helper T-cells (OKT-4+), and suppressor T-cells (OKT-8+) were significantly lower in blood samples obtained from 40 medical students during examinations, compared to baseline values obtained 6 weeks earlier. In addition, the response of T-lymphocytes to stimulation by phytohemagglutinin and concanavilin A was also significantly lower during examinations, compared to baseline. Self-report data documented significantly greater distress associated with examinations. The data have implications for immunosuppressive disorders and stress-related illnesses.
与6周前获取的基线值相比，在考试期间从40名医科学生采集的血样中，总T淋巴细胞（OKT-3+）、辅助性T细胞（OKT-4+）和抑制性T细胞（OKT-8+）的百分比显著降低。此外，与基线相比，考试期间T淋巴细胞对植物血凝素和刀豆球蛋白A刺激的反应也显著降低。自我报告数据显示，考试带来的困扰明显更大。这些数据对免疫抑制性疾病和与压力相关的疾病具有启示意义。
