Halvorsen R, Vassend O
Institute of Transplantation Immunology, National Hospital, Oslo, Norway.
J Psychosom Res. 1987;31(6):693-701. doi: 10.1016/0022-3999(87)90018-3.
The effects of examination stress on some lymphocyte subpopulations and cellular immune responses are reported. Twelve undergraduate students of psychology in examination term were tested six weeks before the written examination (phase I), one day before the first or second examination day (phase II) and 12-14 days after the examination (phase III). A comparable control group of students not in examination was assessed in parallel in phase II. The percentage of circulating monocytes increased in phase II in the examination group whereas the percentage of large (probably activated) CD4 and CD8 cells decreased. There was also a decrease in the number of cells expressing the IL-2 receptor in phase II. The proliferative response of T-cells to antigens, mitogens and allogeneic cells decreased from phase I to phase III. Thus, acute examination stress has a detectable influence on certain cellular immunological functions.
本文报告了考试压力对某些淋巴细胞亚群和细胞免疫反应的影响。选取12名处于考试阶段的心理学专业本科生，在笔试前六周（第一阶段）、第一次或第二次考试前一天（第二阶段）以及考试后12 - 14天（第三阶段）进行测试。在第二阶段，对一个未处于考试状态的可比对照组学生进行了平行评估。考试组在第二阶段循环单核细胞百分比增加，而大的（可能被激活的）CD4和CD8细胞百分比下降。第二阶段表达白细胞介素-2受体的细胞数量也减少。从第一阶段到第三阶段，T细胞对抗原、丝裂原和同种异体细胞的增殖反应降低。因此，急性考试压力对某些细胞免疫功能有可检测到的影响。
