1 Translational Health Research Institute, School of Medicine, Western Sydney University, Penrith, NSW, Australia.
2 Decision Analytics, Sax Institute, Ultimo, NSW, Australia.
Aust N Z J Psychiatry. 2018 Jul;52(7):660-667. doi: 10.1177/0004867417752866. Epub 2018 Jan 23.
This study investigates two approaches to estimate the potential impact of a population-level intervention on Australian suicide, to highlight the importance of selecting appropriate analytic approaches for informing evidence-based strategies for suicide prevention.
The potential impact of a psychosocial therapy intervention on the incidence of suicide in Australia over the next 10 years was used as a case study to compare the potential impact on suicides averted using: (1) a traditional epidemiological measure of population attributable risk and (2) a dynamic measure of population impact based on a systems science model of suicide that incorporates changes over time.
Based on the population preventive fraction, findings suggest that the psychosocial therapy intervention if implemented among all eligible individuals in the Australian population would prevent 5.4% of suicides (or 1936 suicides) over the next 10 years. In comparison, estimates from the dynamic simulation model which accounts for changes in the effect size of the intervention over time, the time taken for the intervention to have an impact in the population, and likely barriers to the uptake and availability of services suggest that the intervention would avert a lower proportion of suicides (between 0.4% and 0.5%) over the same follow-up period.
Traditional epidemiological measures used to estimate population health burden have several limitations that are often understated and can lead to unrealistic expectations of the potential impact of evidence-based interventions in real-world settings. This study highlights these limitations and proposes an alternative analytic approach to guide policy and practice decisions to achieve reductions in Australian suicide.
本研究旨在探讨两种方法来估计人群干预对澳大利亚自杀的潜在影响,以强调为预防自杀选择适当分析方法的重要性,为循证预防自杀策略提供信息。
以心理社会治疗干预对澳大利亚未来 10 年自杀发生率的潜在影响为例,比较使用以下两种方法来估计预防自杀人数的潜在影响:(1)人群归因风险的传统流行病学衡量标准,以及(2)基于自杀系统科学模型的动态人群影响衡量标准,该模型纳入了随时间的变化。
基于人群预防分数,研究结果表明,如果在澳大利亚所有符合条件的人群中实施心理社会治疗干预,未来 10 年内将预防 5.4%的自杀(或 1936 例自杀)。相比之下,考虑到干预效果随时间变化、干预在人群中产生影响所需的时间以及服务的采用和可及性可能存在的障碍的动态模拟模型估计,该干预在同一随访期间可能会预防更少比例的自杀(在 0.4%至 0.5%之间)。
用于估计人群健康负担的传统流行病学方法存在多种局限性,这些局限性往往被低估,可能导致对循证干预措施在现实环境中的潜在影响产生不切实际的期望。本研究强调了这些局限性,并提出了一种替代分析方法,以指导政策和实践决策,实现澳大利亚自杀人数的减少。