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与撒哈拉以南非洲儿童发育迟缓相关的可改变人口风险因素。

Population-Modifiable Risk Factors Associated With Childhood Stunting in Sub-Saharan Africa.

机构信息

Rural Health Research Institute, Charles Sturt University, Orange, New South Wales, Australia.

Charles Darwin University, Menzies School of Health Research, Northern Territory, Australia.

出版信息

JAMA Netw Open. 2023 Oct 2;6(10):e2338321. doi: 10.1001/jamanetworkopen.2023.38321.

Abstract

IMPORTANCE

Identifying modifiable risk factors associated with childhood stunting in sub-Saharan Africa (SSA) is imperative for the development of evidence-based interventions and to achieve the Sustainable Development Goals.

OBJECTIVE

To evaluate key modifiable risk factors associated with childhood stunting in SSA.

DESIGN, SETTING, AND PARTICIPANTS: This cross-sectional study examined the most recent (2014-2021) Demographic and Health Surveys data for children younger than 5 years from 25 SSA countries.

EXPOSURES

Modifiable risk factors included history of diarrhea within 2 weeks, consumption of dairy products, maternal body mass index, maternal educational level, antenatal care visits, place of birth, wealth index, type of toilet, and type of cooking fuel.

MAIN OUTCOMES AND MEASURES

Stunting and severe stunting, measured using the height-for-age z score, were the main outcomes. Children who scored below -2.0 SDs or -3.0 SDs were classified as having stunted or severely stunted growth, respectively. Relative risks and 95% CIs were computed using generalized linear latent and mixed models and log-binomial link functions. Population-attributable fractions (PAFs) were calculated using adjusted relative risks and prevalence estimates for key modifiable risk factors.

RESULTS

This study included 145 900 children from 25 SSA countries. The mean (SD) age of the children was 29.4 (17.3) months, and 50.6% were male. The highest PAFs of severe childhood stunting were observed for mothers lacking a formal education (PAF, 21.9%; 95% CI, 19.0%-24.8%), children lacking consumption of dairy products (PAF, 20.8%; 95% CI, 16.8%-24.9%), unclean cooking fuel (PAF, 9.5%; 95% CI, 2.6%-16.3%), home birth (PAF, 8.3%; 95% CI, 6.3%-10.0%), and low-income household (PAF, 5.8%; 95% CI, 3.4%-8.0%). These 5 modifiable risk factors were associated with 51.6% (95% CI, 40.5%-60.9%) of the severe childhood stunting in SSA.

CONCLUSIONS AND RELEVANCE

This cross-sectional study identified 5 modifiable risk factors that were associated with 51.6% of severe childhood stunting in SSA. These factors should be a priority for policy makers when considering future child health interventions to address chronic malnutrition in SSA.

摘要

重要性

确定与撒哈拉以南非洲(SSA)儿童发育迟缓相关的可改变风险因素对于制定基于证据的干预措施和实现可持续发展目标至关重要。

目的

评估与 SSA 儿童发育迟缓相关的主要可改变风险因素。

设计、设置和参与者:本横断面研究分析了来自 SSA 25 个国家的 5 岁以下儿童最近(2014-2021 年)的人口与健康调查数据。

暴露因素

可改变的风险因素包括在 2 周内腹泻史、乳制品摄入、母亲体重指数、母亲教育水平、产前保健就诊次数、出生地、财富指数、厕所类型和烹饪燃料类型。

主要结果和措施

使用身高年龄 z 评分衡量发育迟缓及严重发育迟缓,这是主要结果。得分低于-2.0 标准差或-3.0 标准差的儿童被归类为生长迟缓或严重生长迟缓。使用广义线性潜在和混合模型以及对数二项式链接函数计算相对风险和 95%置信区间。使用调整后的相对风险和关键可改变风险因素的流行率估计计算人群归因分数(PAF)。

结果

这项研究纳入了来自 SSA 25 个国家的 145900 名儿童。儿童的平均(标准差)年龄为 29.4(17.3)个月,其中 50.6%为男性。严重儿童发育迟缓的最高人群归因分数(PAF)见于缺乏正规教育的母亲(PAF,21.9%;95%CI,19.0%-24.8%)、缺乏乳制品摄入的儿童(PAF,20.8%;95%CI,16.8%-24.9%)、不清洁的烹饪燃料(PAF,9.5%;95%CI,2.6%-16.3%)、在家出生(PAF,8.3%;95%CI,6.3%-10.0%)和低收入家庭(PAF,5.8%;95%CI,3.4%-8.0%)。这 5 个可改变的风险因素与 SSA 51.6%(95%CI,40.5%-60.9%)的严重儿童发育迟缓有关。

结论和相关性

这项横断面研究确定了 5 个与 SSA 51.6%的严重儿童发育迟缓相关的可改变风险因素。在考虑未来在 SSA 开展儿童健康干预措施以解决慢性营养不良问题时,这些因素应该是决策者的优先事项。

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