State Key Laboratory of Molecular Vaccinology and Molecular Diagnostics, School of Public Health, Xiamen University, Xiamen, Fujian, 361102, China.
Key Laboratory of Health Technology Assessment of Fujian Province University, School of Public Health, Xiamen University, Xiamen, Fujian, 361102, China.
Sci Rep. 2018 Jan 24;8(1):1551. doi: 10.1038/s41598-017-17879-w.
This study aimed to examine the association of social engagement (SE) and changes in SE with the risk of dementia among older adults in China. Data were collected from the 2002, 2005, 2008/2009, and 2011/2012 waves of the Chinese Longitudinal Healthy Longevity Survey (CLHLS). Random-effects logistic regression models were used to examine the association of SE and changes in SE with the risk of dementia. Of the 7511 older Chinese adults aged 65 years and over, 338 developed dementia during the 9-year follow-up. SE was associated with dementia risk after adjusting for sociodemographic characteristics, lifestyles and health status (odds ratio (OR) = 0.71, 95% confidence interval (CI) = 0.63-0.81). Participants with consistently high or increased SE had a lower risk of dementia than those with consistently low SE ((OR = 0.14, 95% CI = 0.06-0.28 and OR = 0.33, 95% CI = 0.23-0.48, respectively). Higher SE can reduce the risk of dementia. Furthermore, consistently high or increasing SE is associated with a lower risk of dementia.
本研究旨在探讨社会参与（SE）及其变化与中国老年人痴呆风险之间的关联。数据来自中国老年健康纵向研究（CLHLS）2002、2005、2008/2009 和 2011/2012 年的随访。采用随机效应逻辑回归模型来检验 SE 和 SE 变化与痴呆风险的关联。在 7511 名 65 岁及以上的中国老年人中，338 人在 9 年的随访中出现痴呆。在调整了社会人口特征、生活方式和健康状况后，SE 与痴呆风险相关（优势比（OR）=0.71，95%置信区间（CI）=0.63-0.81）。与持续低 SE 相比，持续高或增加 SE 的参与者患痴呆症的风险较低（OR=0.14，95%CI=0.06-0.28 和 OR=0.33，95%CI=0.23-0.48）。较高的 SE 可以降低痴呆症的风险。此外，持续高或增加 SE 与较低的痴呆风险相关。
