Tsutsumi T, Sekiya S, Osada H, Harumi K, Miyazawa T, Sato S
Jpn Circ J. 1985 Nov;49(11):1159-66. doi: 10.1253/jcj.49.1159.
Vectorcardiograms (VCG) were recorded from five spontaneously hypertensive rats (SHR) and five age-matched normal wistar rats (WR). Arterial systolic blood pressure was 115 +/- 10.8 mmHg in WR and 176 +/- 7.7 mmHg in SHR. The basic procedures for recording VCG in the rat were investigated. After rats were anesthetized with urethane-chloralose, VCG were taken by using the McFee-Parungao lead system in restrained ventral position. VCG in SHR were characterized by superior, posterior and leftward shift of QRS loops, a more elliptical form of QRS loops in the horizontal plane, and an increase in QRS-T angles in all planes, when compared with WR. These vectorcardiographic findings in SHR were quite similar to those produced by left ventricular hypertrophy in humans.
记录了五只自发性高血压大鼠（SHR）和五只年龄匹配的正常Wistar大鼠（WR）的向量心电图（VCG）。WR的动脉收缩压为115±10.8 mmHg，SHR为176±7.7 mmHg。研究了大鼠记录VCG的基本程序。用乌拉坦-氯醛糖麻醉大鼠后，采用McFee-Parungao导联系统在约束腹位记录VCG。与WR相比，SHR的VCG特征为QRS环向上、向后和向左移位，水平面QRS环呈更椭圆的形态，所有平面的QRS-T角增大。SHR的这些向量心电图表现与人类左心室肥厚产生的表现非常相似。
