Sun Yating, Ma Shiyang, Fang Li, Wang Jinhai, Dong Lei
Department of Gastroenterology, the Second Affiliated Hospital of Xi'an Jiaotong University, No. 157 Xiwu Road, Xi'an, Shaanxi, 710004, China.
Endoscopy Center, Ankang People's Hospital, Ankang, 401147, China.
BMC Gastroenterol. 2018 Jan 25;18(1):17. doi: 10.1186/s12876-018-0745-7.
The diagnosis of Barrett's esophagus (BE) is disturbed by numerous factors, including correct gastroesophageal junction judgment, the initial location of the Z-line and the biopsy result above it. The acetic acid (AA) could help to diagnose BE better than high resolution imaging technology or magnifying endoscopy, by providing enhanced contrast of different epithelium. We have noticed AA could produce multiple white circular lines, forming circular stripes (CS), at lower esophagus, which hasn't been reported by others. This study aimed to investigate whether the CS is a special marker in BE patients.
A total of 47 BE patients and 63 healthy people were enrolled from March 2016 to October 2016, and 2% AA staining had been operated routinely at lower esophagus under high resolution gastroscopy. We observed whether there were CS after AA staining and the images were compared between the two groups.
CS were confirmed in 42 patients (89.36%) in the BE group and 5 (7.94) in the control group ((χ = 72.931, P < 0.001)). The average width of CS was 0.76 ± 0.25 cm in BE group, which was similar to that in the control group (0.88 ± 0.11 cm). Villous or punctate or reticular pattern usually existed above or below the CS.
CS could be found at lower esophagus in most BE patients with AA staining, and this special feature might be valuable in diagnosing, evaluating and following up of BE patients.
巴雷特食管（BE）的诊断受到多种因素干扰，包括胃食管交界的正确判断、Z线的初始位置及其上方的活检结果。乙酸（AA）通过增强不同上皮的对比度，在诊断BE方面可能比高分辨率成像技术或放大内镜更好。我们注意到AA可在食管下段产生多条白色环线，形成环形条纹（CS），这尚未见其他人报道。本研究旨在探讨CS是否为BE患者的一种特殊标志物。
2016年3月至2016年10月共纳入47例BE患者和63名健康人，在高分辨率胃镜下对食管下段常规进行2% AA染色。观察AA染色后是否存在CS，并比较两组图像。
BE组42例患者（89.36%）出现CS，对照组5例（7.94%）出现CS（χ² = 72.931，P < 0.001）。BE组CS的平均宽度为0.76 ± 0.25 cm，与对照组（0.88 ± 0.11 cm）相似。CS上方或下方通常存在绒毛状、点状或网状图案。
大多数BE患者食管下段AA染色时可发现CS，这一特殊特征可能对BE患者的诊断、评估和随访有价值。
