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快餐、甜食和饮料消费与结直肠癌风险:约旦的一项病例对照研究

Fast Foods, Sweets and Beverage Consumption and Risk of Colorectal Cancer: A Case-Control Study in Jordan.

作者信息

Tayyem Reema F, Bawadi Hiba A, Shehadah Ihab, Bani-Hani Kamal E, Takruri Hamed, Al-Jaberi Tareq, Heath Dennis D

机构信息

The University of Jordan, Faculty of Agriculture, Amman, Jordan. Email:

出版信息

Asian Pac J Cancer Prev. 2018 Jan 27;19(1):261-269. doi: 10.22034/APJCP.2018.19.1.261.

Abstract

Background: The effects of consuming fast foods, sweets and beverages on the development of colorectal cancer (CRC) are unclear. The aim of this case-control study was to assess possible associations between the consumption of different fast foods, sweets and beverages and CRC risk in a Jordanian population. Methods: Two hundred and twenty diagnosed CRC cases and 281 controls were enrolled. Diet history was obtained using a validated quantitative questionnaire. Results: Consumption of some types of fast food, and particularly falafel, was associated with an increased risk of developing CRC. Elevated risk was found for potato and corn chips with an AOR of 4.36 (95%CI: 1.24-15.28) for daily consumption and 3.33 (95%CI: 1.00-11.11) for ≥5 servings/week. Consuming 1-2 or >5 servings per week of fried potatoes or 2-3 servings per week of chicken in sandwiches also increased the risk while exposure to fresh tomato juice and hot pepper sauce on a monthly basis appeared to exert a protective effect. Conclusions: Consumption of fried fast food items was significantly linked with an increased risk of developing CRC in Jordan.

摘要

背景

食用快餐、甜食和饮料对结直肠癌(CRC)发生发展的影响尚不清楚。本病例对照研究的目的是评估约旦人群中不同快餐、甜食和饮料的消费与CRC风险之间的可能关联。方法:纳入220例确诊的CRC病例和281例对照。使用经过验证的定量问卷获取饮食史。结果:食用某些类型的快餐,尤其是炸豆丸子,与患CRC的风险增加有关。发现食用土豆和玉米片会增加风险,每日食用的调整后比值比(AOR)为4.36(95%置信区间:1.24 - 15.28),每周食用≥5份的AOR为3.33(95%置信区间:1.00 - 11.11)。每周食用1 - 2份或>5份炸土豆或每周食用2 - 3份鸡肉三明治也会增加风险,而每月饮用新鲜番茄汁和食用辣椒酱似乎具有保护作用。结论:在约旦,食用油炸快餐食品与患CRC的风险增加显著相关。

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