Shapiro Bryan B, Hedrick Rebecca, Vanle Brigitte C, Becker Courtney A, Nguyen Chris, Underhill David M, Morgan Margie A, Kopple Joel D, Danovitch Itai, IsHak Waguih William
Department of Psychiatry and Human Behavior, UC Irvine Medical Center, Orange, California, USA.
Department of Psychiatry and Behavioral Neurosciences, Cedars-Sinai Medical Center, Los Angeles, California, USA.
BMJ Case Rep. 2018 Jan 26;2018:bcr-2017-221435. doi: 10.1136/bcr-2017-221435.
Cryptococcal meningitis is a life-threatening condition most commonly observed in immunocompromised individuals. We describe a daily cannabis smoker without evidence of immunodeficiency presenting with confirmed meningitis. An investigation of cannabis samples from the patient's preferred dispensary demonstrated contamination with several varieties of , including , and other opportunistic fungi. These findings raise concern regarding the safety of dispensary-grade cannabis, even in immunocompetent users.
隐球菌性脑膜炎是一种危及生命的疾病，最常见于免疫功能低下的个体。我们描述了一名每日吸食大麻的人，他没有免疫缺陷的证据，但却出现了确诊的脑膜炎。对该患者首选药房的大麻样本进行调查发现，其受到了包括新型隐球菌和其他机会性真菌在内的多种真菌的污染。这些发现引发了人们对药房级大麻安全性的担忧，即使是免疫功能正常的使用者也不例外。
